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1.发明公开NOUVEAUX SUBSTRATS D' O6-ALKYLGUANINE-ADN ALKYLTRANSFERASE ET SES MUTANTS 有权NOUVEAUX底物D'O6-ALKYL鸟嘌呤-ADN烷基转移酶和ET突变体突变体
公开(公告)号：EP2331510A1
公开(公告)日：2011-06-15
申请号：EP09748424.0
申请日：2009-09-22
发明人： BOURRIER, Emmanuel , LAGET, Michel , LAMARQUE, Laurent , TINEL, Norbert , TRINQUET, Eric , BAZIN, Hervé
IPC分类号： C07D239/36 , C07D239/47 , C07D239/54 , C07D403/12 , C07D473/04 , C07D473/18 , C07D473/30
CPC分类号： C07D239/47 , C07D403/14 , C07D473/18 , C07D487/18 , C07D519/00
摘要： The invention relates to compounds of the formula (I’) where A, L
2 , M and B are such as defined in the description. Said compounds consist of substrates of O
6 -alkylguanine-DNA alkyltransferase and mutants thereof.摘要翻译： 本发明涉及式（I'）的化合物，其中A，L 2，M和B如说明书中所定义。 所述化合物由O6-烷基鸟嘌呤-DNA烷基转移酶及其突变体的底物组成。
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2.发明公开METHODE DE DETECTION D'INTERACTION INTRACELLULAIRE ENTRE BIO-MOLECULES 审中-公开试剂盒和方法用于检测生物分子的细胞内之间相互作用的
公开(公告)号：EP1929294A2
公开(公告)日：2008-06-11
申请号：EP06808277.5
申请日：2006-09-04
发明人： PRIBILLA, Iris , BAZIN, Hervé , GHOSE, Sraboni , TINEL, Norbert , FINK, Michel , TRINQUET, Eric , MATHIS, Gérard
CPC分类号： G01N33/542
摘要： The invention concerns a quantitative non-microscopic method for detecting intracellular interaction between biomolecules, on living cells, responsive to a biological or pharmacological stimulation, by time-resolved proximate energy transfer effect between a fluorescence donor/acceptor pair. The invention is useful for high throughput screening of molecules and intracellular signalling pathway detection.
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