-
1.发明授权T CELL RECEPTOR PEPTIDES AS THERAPEUTICS FOR AUTOIMMUNE AND MALIGNANT DISEASE 失效T细胞受体肽作为治疗剂自身免疫疾病和恶性病变
公开(公告)号：EP0552142B2
公开(公告)日：2003-12-17
申请号：EP90911332.6
申请日：1990-07-19
IPC分类号： C07K7/04 , C07K14/47 , C07K14/725 , C07K16/28 , C07K1/00 , A61K38/03 , A61K38/17 , C12P21/04
CPC分类号： C07K16/2809 , A61K38/00 , C07K14/7051
摘要： Peptides and pharmaceutical compositions comprising immunogenic peptides of a marker T cell receptor (TCR) characteristic of an immune-related disease, capable of preventing, suppressing, or treating the disease, are disclosed. In a preferred embodiment, the amino acid sequence of the peptide corresponds to at least part of a complementary determining region (CDR) or a hypervariable region of the TCR. Antibodies and/or T cells immunologically reactive to the TCR peptide capable of preventing, suppressing, or treating an immune-related disease by passive transfer are also disclosed.
-
2.发明授权T CELL RECEPTOR PEPTIDES AS THERAPEUTICS FOR AUTOIMMUNE AND MALIGNANT DISEASE 失效T细胞受体肽作为治疗剂自身免疫疾病和恶性病变
公开(公告)号：EP0552142B1
公开(公告)日：1998-01-07
申请号：EP90911332.6
申请日：1990-07-19
IPC分类号： C07K7/04 , C07K14/47 , C07K14/725 , C07K16/28 , C07K1/00 , A61K38/03 , A61K38/17 , C12P21/04
CPC分类号： C07K16/2809 , A61K38/00 , C07K14/7051
摘要： Peptides and pharmaceutical compositions comprising immunogenic peptides of a marker T cell receptor (TCR) characteristic of an immune-related disease, capable of preventing, suppressing, or treating the disease, are disclosed. In a preferred embodiment, the amino acid sequence of the peptide corresponds to at least part of a complementary determining region (CDR) or a hypervariable region of the TCR. Antibodies and/or T cells immunologically reactive to the TCR peptide capable of preventing, suppressing, or treating an immune-related disease by passive transfer are also disclosed.
-
搜索结果
2 条记录 (耗时 0.019 秒)
