公开(公告)号：EP0804452A4

公开(公告)日：1998-08-12

申请号：EP94925135

申请日：1994-07-26

申请人： COR THERAPEUTICS INC

发明人： SCARBOROUGH ROBERT M ,  SUNDELIN JOHAN

IPC分类号： C12N15/09 ,  A61K38/00 ,  A61K48/00 ,  C07H21/04 ,  C07K7/06 ,  C07K7/08 ,  C07K14/705 ,  C07K14/72 ,  C07K16/28 ,  C12N5/10 ,  C12P21/02 ,  C12R1/91 ,  C07H21/00 ,  C07K2/00 ,  C07K7/00

CPC分类号： C07K7/06 ,  A61K38/00 ,  A61K48/00 ,  C07K7/08 ,  C07K14/723

摘要： The DNA encoding the C140 cell surface receptor has been cloned and sequenced. The availability of this DNA permits the recombinant production of the C140 receptor which can be produced at cell or oocyte surfaces and is useful in assay systems both for the detection of substances which affect its activity, including agonists and antagonists. Further, the elucidation of the structure of the C140 receptor permits the design of agonist and antagonist compounds which are useful in these assays. The availability of the C140 receptor also permits production of antibodies specifically immunoreactive with the receptor per se or with specific regions thereof.

公开(公告)号：EP0870198A4

公开(公告)日：2001-04-04

申请号：EP96904515

申请日：1996-01-25

申请人： COR THERAPEUTICS INC

发明人： SUNDELIN JOHAN ,  SCARBOROUGH ROBERT M

IPC分类号： C12N15/09 ,  A61K31/00 ,  A61K31/70 ,  A61K31/7088 ,  A61K38/00 ,  A61K48/00 ,  A61P43/00 ,  C07H21/04 ,  C07K7/02 ,  C07K14/72 ,  C07K16/28 ,  C12N5/10 ,  C12N15/00 ,  C12P21/02 ,  C12P21/08 ,  C12Q1/68 ,  C12R1/91 ,  G01N33/15 ,  G01N33/53 ,  G01N33/566 ,  A61K38/04 ,  A61K51/00 ,  C07H15/00 ,  C07K1/00 ,  C12N1/20 ,  C12N5/00 ,  C12P21/06

CPC分类号： C07K14/723 ,  A61K38/00 ,  A61K48/00