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1.发明授权HEMATOLOGY CONTROL COMPOSITIONS FOR THREE POPULATIONS OF LEUKOCYTES, AND METHODS FOR THEIR PREPARATION AND USE IN WHOLE BLOOD CONTROL SYSTEMS 失效白血病三种人群的血液学控制组合物及其制备和使用全血控制系统的方法
公开(公告)号：EP0181393B1
公开(公告)日：1992-09-09
申请号：EP85902765.8
申请日：1985-05-07
申请人： COULTER CORPORATION
IPC分类号： G01N33/48
CPC分类号： G01N33/96 , G01N2496/05 , Y10T436/101666 , Y10T436/105831 , Y10T436/106664 , Y10T436/107497 , Y10T436/108331
摘要： This invention primarily is directed to a hematology reference control solution, the three separate white cell controll portions thereof consisting of three types of fixed red cells of determined size distribution for checking the operation of a particle analyzing instrument, including its predetermined lower and upper threshold settings for each class or subclass of leukocytes. For preparing a human granulocyte analogue, nurse shark erythrocytes are altered and fixed in a chilled solution to simulate in number, size and distribution the granulocytes in human whole blood. Such a granulocyte analogue is useful as a free-standing reference control, for determination of human granulocytes only, or can be comingled with reference controls for lymphocytes and mononuclear cells for use with multi-parameter instruments to give a trimodal leukocyte reference control, which itself can be included in a multiple-analysis hematology reference control, having components for also determining red blood cell and platelet parameters.
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