公开(公告)号：EP2007408A2

公开(公告)日：2008-12-31

申请号：EP07705971.5

申请日：2007-02-28

申请人： CSIR

发明人： HORAK, Roelof, Marthinus ,  WADIWALA, Ebrahim ,  FOUCHE, Gerda ,  VAN DER MERWE, Marina, Mikhailovna ,  MAHARAJ, Vinesh, Jaichand ,  ACKERMAN, Louis, Gabriel, Jozua

IPC分类号： A61K36/906 ,  A61K31/343 ,  A61P11/06 ,  A61P17/04 ,  A61P27/14

CPC分类号： A61K36/906 ,  A61K31/343

摘要： The invention provides the use of at least one plant selected from plants of the family Zingiberaceae in the preparation of a medicament for use in the treatment or prophylaxis of allergic diseases. The plant is optionally selected from the genera Siphonochilus, Kaempferia, Cienkowskia and Cienkowskiella and the species is optionally selected from Siphonochilus aethiopicus, Siphonochilus natalensis, Kaempferia aethiopica, Kaempferia natalensis, Kaempferia ethelae, Cienkowskia aethiopica and Cienkowskiella aethiopica. The allergic disease is selected from asthma and atopy.

公开(公告)号：EP2007408B1

公开(公告)日：2019-05-01

申请号：EP07705971.5

申请日：2007-02-28

申请人： CSIR

发明人： HORAK, Roelof, Marthinus ,  WADIWALA, Ebrahim ,  FOUCHE, Gerda ,  VAN DER MERWE, Marina, Mikhailovna ,  MAHARAJ, Vinesh, Jaichand ,  ACKERMAN, Louis, Gabriel, Jozua

IPC分类号： A61K36/906 ,  A61K31/343 ,  A61P11/06 ,  A61P17/04 ,  A61P27/14

公开(公告)号：EP2214688A2

公开(公告)日：2010-08-11

申请号：EP08737763.6

申请日：2008-04-08

申请人： CSIR

发明人： FOUCHE, Gerda ,  MAHARAJ, Vinesh, Jaichand ,  MTHEMBU, Xolani ,  ACKERMAN, Louis ,  VAN DER MERWE, Marina

IPC分类号： A61K36/48 ,  A61P13/08

CPC分类号： A61K36/48

摘要： The invention provides the use of an extract of a plant of the genus Elephantorrhiza and at least one compound selected from quercitin-3′-O-glucoside, trans-3-O-galloyl-3,3′,5,5′,7-pentahydroxyflavan, taxifolin-3′-O-glucoside, catechin and epicatechin in the preparation of a medicament for the treatment of benign prostatic hyperplasia (BPH). The mode of action is by a route selected from blocking the conversion of testosterone to dihydrotestosterone by inhibiting the 5α-reductase enzyme or by reducing oxidative stress or both.

公开(公告)号：EP2214688B1

公开(公告)日：2018-09-05

申请号：EP08737763.6

申请日：2008-04-08

申请人： CSIR

发明人： FOUCHE, Gerda ,  MAHARAJ, Vinesh, Jaichand ,  MTHEMBU, Xolani ,  ACKERMAN, Louis ,  VAN DER MERWE, Marina

IPC分类号： A61K36/48 ,  A61P13/08

CPC分类号： A61K36/48

摘要： The invention provides the use of an extract of a plant of the genus Elephantorrhiza and at least one compound selected from quercitin-3′-O-glucoside, trans-3-O-galloyl-3,3′,5,5′,7-pentahydroxyflavan, taxifolin-3′-O-glucoside, catechin and epicatechin in the preparation of a medicament for the treatment of benign prostatic hyperplasia (BPH). The mode of action is by a route selected from blocking the conversion of testosterone to dihydrotestosterone by inhibiting the 5α-reductase enzyme or by reducing oxidative stress or both.

公开(公告)号：EP2037913B1

公开(公告)日：2016-07-20

申请号：EP07736000.6

申请日：2007-05-23

申请人： CSIR

发明人： FOUCHE, Gerda ,  KHOROMBI, Eric ,  MAHARAJ, Vinesh, Jaichand

IPC分类号： A61K31/365 ,  A61K36/185

CPC分类号： A61K36/185 ,  A61K31/365

公开(公告)号：EP2037913A2

公开(公告)日：2009-03-25

申请号：EP07736000.6

申请日：2007-05-23

申请人： CSIR

发明人： FOUCHE, Gerda ,  KHOROMBI, Eric ,  MAHARAJ, Vinesh, Jaichand

IPC分类号： A61K31/365 ,  A61K36/185

CPC分类号： A61K36/185 ,  A61K31/365

摘要： A process for the production of a substance or composition for the therapeutic or prophylactic treatment of erectile dysfunction or the enhancement of libido in a male human or animal subject comprises the step of formulating the substance or composition from at least one of plant material and an extract of plant material of at least one plant species of the family Geraniaceae.