公开(公告)号：EP4286381A2

公开(公告)日：2023-12-06

申请号：EP23204042.8

申请日：2017-08-09

申请人： Celgene Quanticel Research, Inc.

发明人： XU, Jiangchun ,  CHO, Robert ,  NGUYEN, Aaron

IPC分类号： C07D405/14

摘要： Methods are provided for the treatment of relapsed and/or refractory solid tumors (including neuroendocrine carcinomas (NEC)) and non-Hodgkin's lymphomas (NHLs) and the like, using substituted heterocyclic derivative compounds and pharmaceutical compositions comprising compounds useful for the inhibition of lysine specific demethylase-1 (LSD-1).

公开(公告)号：EP4286381A3

公开(公告)日：2024-02-28

申请号：EP23204042.8

申请日：2017-08-09

申请人： Celgene Quanticel Research, Inc.

发明人： XU, Jiangchun ,  CHO, Robert ,  NGUYEN, Aaron

IPC分类号： A61K31/513 ,  A61K31/7048 ,  A61K31/357 ,  A61K31/436 ,  A61K31/551 ,  A61K31/5685 ,  A61K31/5377 ,  A61P35/00 ,  C07D401/14 ,  C07D405/14 ,  C07D401/04

摘要： Methods are provided for the treatment of relapsed and/or refractory solid tumors (including neuroendocrine carcinomas (NEC)) and non-Hodgkin's lymphomas (NHLs) and the like, using substituted heterocyclic derivative compounds and pharmaceutical compositions comprising compounds useful for the inhibition of lysine specific demethylase-1 (LSD-1).