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公开(公告)号：EP3760216A1
公开(公告)日：2021-01-06
申请号：EP20186934.4
申请日：2011-07-25
申请人： Cellestis Limited
IPC分类号： A61K38/16 , C07K14/35 , C07K16/12 , C12N5/00 , C12Q1/68 , G01N33/569 , A61K38/10 , G01N33/68
摘要： The present invention refers to the use of gene sequences or portions thereof characterized in that the same belong to the classes of in vitro and ex vivo induced, repressed or conserved genes in Mycobacterium tuberculosis currently infected human macrophages and to corresponding peptides or consensus peptides or proteins for the preparation of specific bio-markers for the diagnosis and prevention of active or latent disease.
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公开(公告)号：EP3388071A1
公开(公告)日：2018-10-17
申请号：EP18174953.2
申请日：2011-07-25
申请人： Cellestis Limited
IPC分类号： A61K38/16 , C07K14/35 , C07K16/12 , C12N5/00 , C12Q1/68 , G01N33/569 , A61K38/10 , G01N33/68
CPC分类号： G01N33/56972 , A61K38/10 , A61K38/164 , C07K7/08 , C07K14/35 , G01N33/5695 , G01N33/6866 , G01N2333/35 , G01N2333/57
摘要： The present invention refers to the use of gene sequences or portions thereof characterized in that the same belong to the classes of in vitro and ex vivo induced, repressed or conserved genes in Mycobacterium tuberculosis currently infected human macrophages and to corresponding peptides or consensus peptides or proteins for the preparation of specific bio-markers for the diagnosis and prevention of active or latent disease.
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3.发明授权
公开(公告)号：EP2595645B1
公开(公告)日：2016-11-09
申请号：EP11754756.2
申请日：2011-07-25
申请人： Cellestis Limited
CPC分类号： G01N33/56972 , A61K38/10 , A61K38/164 , C07K7/08 , C07K14/35 , G01N33/5695 , G01N33/6866 , G01N2333/35 , G01N2333/57
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公开(公告)号：EP4005584A1
公开(公告)日：2022-06-01
申请号：EP22150479.8
申请日：2011-07-25
申请人： Cellestis Limited
IPC分类号： A61K38/16 , C07K14/35 , C07K16/12 , C12N5/00 , C12Q1/68 , G01N33/569 , A61K38/10 , G01N33/68
摘要： Use of amino acid sequences from Mycobacterium tuberculosis or corresponding nucleic acids for diagnosis and prevention of tubercular infection, diagnostic kit and vaccine therefrom.
The present invention refers to the use of gene sequences or portions thereof characterized in that the same belong to the classes of in vitro and ex vivo induced, repressed or conserved genes in Mycobacterium tuberculosis currently infected human macrophages and to corresponding peptides or consensus peptides or proteins for the preparation of specific bio-markers for the diagnosis and prevention of active or latent disease.-
5.发明公开USE OF AMINO ACID SEQUENCES FROM MYCOBACTERIUM TUBERCULOSIS OR CORRESPONDING NUCLEIC ACIDS FOR DIAGNOSIS AND PREVENTION OF TUBERCULAR INFECTION, DIAGNOSTIC KIT AND VACCINE THEREFROM 有权氨基酸序列的来自结核分枝杆菌或相关NUCLEIC用于诊断和结核病感染的预防，诊断试剂盒和疫苗及其使用
公开(公告)号：EP2949337A3
公开(公告)日：2016-01-20
申请号：EP15177138.3
申请日：2011-07-25
申请人： Cellestis Limited
IPC分类号： A61K38/16 , C07K14/35 , C07K16/12 , C12N5/00 , C12Q1/68 , G01N33/569 , A61K38/10 , G01N33/68
CPC分类号： G01N33/56972 , A61K38/10 , A61K38/164 , C07K7/08 , C07K14/35 , G01N33/5695 , G01N33/6866 , G01N2333/35 , G01N2333/57
摘要： The present invention refers to the use of gene sequences or portions thereof characterized in that the same belong to the classes of in vitro and ex vivo induced, repressed or conserved genes in Mycobacterium tuberculosis currently infected human macrophages and to corresponding peptides or consensus peptides or proteins for the preparation of specific bio-markers for the diagnosis and prevention of active or latent disease.
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6.发明公开USE OF AMINO ACID SEQUENCES FROM MYCOBACTERIUM TUBERCULOSIS OR CORRESPONDING NUCLEIC ACIDS FOR DIAGNOSIS AND PREVENTION OF TUBERCULAR INFECTION, DIAGNOSTIC KIT AND VACCINE THEREFROM 有权氨基酸序列的来自结核分枝杆菌或相关NUCLEIC用于诊断和结核病感染的预防，诊断试剂盒和疫苗及其使用
公开(公告)号：EP2949337A2
公开(公告)日：2015-12-02
申请号：EP15177138.3
申请日：2011-07-25
申请人： Cellestis Limited
IPC分类号： A61K38/16 , C07K14/35 , C07K16/12 , C12N5/00 , C12Q1/68 , G01N33/569 , A61K38/10 , G01N33/68
CPC分类号： G01N33/56972 , A61K38/10 , A61K38/164 , C07K7/08 , C07K14/35 , G01N33/5695 , G01N33/6866 , G01N2333/35 , G01N2333/57
摘要： The present invention refers to the use of gene sequences or portions thereof characterized in that the same belong to the classes of in vitro and ex vivo induced, repressed or conserved genes in Mycobacterium tuberculosis currently infected human macrophages and to corresponding peptides or consensus peptides or proteins for the preparation of specific bio-markers for the diagnosis and prevention of active or latent disease.
摘要翻译： 本发明涉及使用基因序列或在做了同样的它们的特征的部分的属于的体外和类离体诱导，在结核分枝杆菌抑制或保守的基因目前感染的人巨噬细胞和相应的肽或共有的肽或蛋白质 对于特定的生物标志物为活动性或潜伏性疾病的诊断和预防的制备。
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公开(公告)号：EP3597210A1
公开(公告)日：2020-01-22
申请号：EP19190545.4
申请日：2011-07-25
申请人： Cellestis Limited
IPC分类号： A61K38/16 , C07K14/35 , C07K16/12 , C12N5/00 , C12Q1/68 , G01N33/569 , A61K38/10 , G01N33/68
摘要： Use of amino acid sequences from Mycobacterium tuberculosis or corresponding nucleic acids for diagnosis and prevention of tubercular infection, diagnostic kit and vaccine therefrom.
The present invention refers to the use of gene sequences or portions thereof characterized in that the same belong to the classes of in vitro and ex vivo induced, repressed or conserved genes in Mycobacterium tuberculosis currently infected human macrophages and to corresponding peptides or consensus peptides or proteins for the preparation of specific bio-markers for the diagnosis and prevention of active or latent disease.-
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9.发明公开USE OF AMINO ACID SEQUENCES FROM MYCOBACTERIUM TUBERCULOSIS OR CORRESPONDING NUCLEIC ACIDS FOR DIAGNOSIS AND PREVENTION OF TUBERCULAR INFECTION, DIAGNOSTIC KIT AND VACCINE THEREFROM 有权氨基酸序列的来自结核分枝杆菌或相关NUCLEIC用于诊断和结核感染预防，试剂盒诊断和疫苗及其使用
公开(公告)号：EP2595645A2
公开(公告)日：2013-05-29
申请号：EP11754756.2
申请日：2011-07-25
申请人： Cellestis Limited
CPC分类号： G01N33/56972 , A61K38/10 , A61K38/164 , C07K7/08 , C07K14/35 , G01N33/5695 , G01N33/6866 , G01N2333/35 , G01N2333/57
摘要： The present invention refers to the use of gene sequences or portions thereof characterized in that the same belong to the classes of in vitro and ex vivo induced, repressed or conserved genes in Mycobacterium tuberculosis currently infected human macrophages and to corresponding peptides or consensus peptides or proteins for the preparation of specific bio-markers for the diagnosis and prevention of active or latent disease.
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公开(公告)号：EP2949337B1
公开(公告)日：2018-07-04
申请号：EP15177138.3
申请日：2011-07-25
申请人： Cellestis Limited
IPC分类号： A61K38/16 , C07K14/35 , C07K16/12 , C12N5/00 , C12Q1/68 , G01N33/569 , A61K38/10 , G01N33/68
CPC分类号： G01N33/56972 , A61K38/10 , A61K38/164 , C07K7/08 , C07K14/35 , G01N33/5695 , G01N33/6866 , G01N2333/35 , G01N2333/57
摘要： The present invention refers to the use of gene sequences or portions thereof characterized in that the same belong to the classes of in vitro and ex vivo induced, repressed or conserved genes in Mycobacterium tuberculosis currently infected human macrophages and to corresponding peptides or consensus peptides or proteins for the preparation of specific bio-markers for the diagnosis and prevention of active or latent disease.
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