专利检索 ap:("Cellzome Limited") AND inv:"LADDUWAHETTY, Tammy" 第 1 页

1.

发明授权
{(4-(4-MORPHOLINO-DIHYDROTHIENO[3,4-D]PYRIMIDIN-2-YL)ARYL}UREA OR CARBAMATE DERIVATIVES AS MTOR INHIBITORS 有权
标题翻译： {（4-（4-吗啉代二氢 - 噻吩并[3,4-d]嘧啶-2-基）芳基}脲或氨基甲酸酯衍生物ALS mTOR抑制剂

公开(公告)号：EP2763985B1

公开(公告)日：2016-06-22

申请号：EP12769098.0

申请日：2012-10-05

申请人： Cellzome Limited

发明人： LYNCH, Rosemary , CANSFIELD, Andrew David , HARDY, Daniel Paul , FEUTRILL, John Thomas , ADREGO, Rita , ELLARD, Katie , LADDUWAHETTY, Tammy

IPC分类号： C07D495/04 , A61K31/519 , A61P29/00 , A61P37/00 , A61P31/12 , A61P35/00 , A61P25/28

CPC分类号： C07D495/04 , A61K31/519 , A61K31/5377 , A61K31/5386 , C07D417/02 , C07D498/08

2.

发明公开
MORPHOLINO SUBSTITUTED BICYCLIC PYRIMIDINE UREA OR CARBAMATE DERIVATIVES AS MTOR INHIBITORS 有权
标题翻译： {（4-（4-吗啉代二氢 - 噻吩并[3,4-d]嘧啶-2-基）芳基}脲或氨基甲酸酯衍生物ALS mTOR抑制剂

公开(公告)号：EP2763985A1

公开(公告)日：2014-08-13

申请号：EP12769098.0

申请日：2012-10-05

申请人： Cellzome Limited

发明人： LYNCH, Rosemary , CANSFIELD, Andrew David , HARDY, Daniel Paul , FEUTRILL, John Thomas , ADREGO, Rita , ELLARD, Katie , LADDUWAHETTY, Tammy

IPC分类号： C07D417/02 , A61K31/519

CPC分类号： C07D495/04 , A61K31/519 , A61K31/5377 , A61K31/5386 , C07D417/02 , C07D498/08

摘要： The invention relates to compounds of formula (I) wherein m, o, R
a , R
b , R
1 and T
1 have the meaning as cited in the description and the claims. Said compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the use as medicaments.