专利检索 ap:("Centre National de la Recherche Scientifique" OR "Université de Strasbourg") AND inv:"BROWN, Richard, C., D." 第 1 页

1.

发明授权
BROAD SPECTRUM REACTIVATORS OF OPNA-INHIBITION OF HUMAN CHOLINESTERASES 有权

公开(公告)号：EP3331859B1

公开(公告)日：2019-10-02

申请号：EP16747883.3

申请日：2016-07-29

申请人： Centre National de la Recherche Scientifique , Université de Strasbourg

发明人： BAATI, Rachid , BROWN, Richard, C., D. , DIAS, José , NACHON, Florian , DE SOUSA, Julien

IPC分类号： C07D213/74 , C07D401/12 , A61K31/4709 , A61P25/00

2.

发明公开
BROAD SPECTRUM REACTIVATORS OF OPNA-INHIBITION OF HUMAN CHOLINESTERASES 审中-公开

公开(公告)号：EP3331859A1

公开(公告)日：2018-06-13

申请号：EP16747883.3

申请日：2016-07-29

申请人： Centre National de la Recherche Scientifique , Université de Strasbourg

发明人： BAATI, Rachid , BROWN, Richard, C., D. , DIAS, José , NACHON, Florian , DE SOUSA, Julien

IPC分类号： C07D213/74 , C07D401/12 , A61K31/4709 , A61P25/00

CPC分类号： C07D401/12 , C07D213/74

摘要： The present invention deals with novel compounds which are reactivators of human acetylcholinesterase, pharmaceutical compositions comprising said compounds, and their use in the treatment of a nervous and/or respiratory failure due to intoxication with at least one organophosphorous nerve agent such as warfare agents and pesticides. It also pertains to these compounds for use in the treatment of neurological diseases such as Alzheimer's disease.