公开(公告)号：EP2376491B1

公开(公告)日：2015-03-04

申请号：EP09775073.1

申请日：2009-12-21

申请人： Cephalon, Inc.

发明人： BRESLIN, Henry J. ,  CHATTERJEE, Sankar ,  DIEBOLD, James L. ,  DORSEY, Bruce D. ,  DUNN, Derek ,  GINGRICH, Diane E. ,  HOSTETLER, Greg A. ,  HUDKINS, Robert L. ,  HUNTER, Rachael ,  JOSEF, Kurt ,  LISKO, Joseph ,  MESAROS, Eugen F. ,  MILKIEWICZ, Karen L. ,  OTT, Gregory R. ,  SUNDAR, Babu G. ,  THEROFF, Jay P. ,  THIEU, Tho ,  TRIPATHY, Rabindranath ,  UNDERINER, Theodore L. ,  WEINBERG, Linda ,  WELLS, Gregory J. ,  ZIFICSAK, Craig A.

IPC分类号： C07D487/04 ,  A61K31/53 ,  A61P35/00

CPC分类号： C07D487/04

公开(公告)号：EP2376491A1

公开(公告)日：2011-10-19

申请号：EP09775073.1

申请日：2009-12-21

申请人： Cephalon, Inc.

发明人： BRESLIN, Henry J. ,  CHATTERJEE, Sankar ,  DIEBOLD, James L. ,  DORSEY, Bruce D. ,  DUNN, Derek ,  GINGRICH, Diane E. ,  HOSTETLER, Greg A. ,  HUDKINS, Robert L. ,  HUNTER, Rachael ,  JOSEF, Kurt ,  LISKO, Joseph ,  MESAROS, Eugen F. ,  MILKIEWICZ, Karen L. ,  OTT, Gregory R. ,  SUNDAR, Babu G. ,  THEROFF, Jay P. ,  THIEU, Tho ,  TRIPATHY, Rabindranath ,  UNDERINER, Theodore L. ,  WEINBERG, Linda ,  WELLS, Gregory J. ,  ZIFICSAK, Craig A.

IPC分类号： C07D487/04 ,  A61K31/53 ,  A61P35/00

CPC分类号： C07D487/04

摘要： The present invention provides a compound of formula (I) or a salt form thereof, wherein Q
1 , Q
2 , Q
3 , and Q
4 are as defined herein. The compound of formula (I) has ALK and/or JAK2 inhibitory activity, and may be used to treat proliferative disorders.