公开(公告)号：EP3590944A1

公开(公告)日：2020-01-08

申请号：EP18760796.5

申请日：2018-02-28

申请人： Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

发明人： XIONG, Jian ,  XIE, Cheng ,  CHEN, Kevin X ,  XU, Xiongbin ,  ZHANG, Xuejin ,  GONG, Zhen ,  LI, Jian ,  CHEN, Shuhui ,  ZHANG, Aiming ,  JIANG, Zhulian ,  ZHANG, Xiquan ,  TIAN, Xin

IPC分类号： C07F5/02 ,  A61K31/69 ,  A61P35/00

摘要： Disclosed in the present application are a compound represented by formula (I), or a pharmaceutically acceptable salt, a tautomer thereof, a stereoisomer thereof, or a geometrical isomer thereof, and uses thereof in the preparation of drugs for treating or preventing multiple myeloma.

公开(公告)号：EP3805223A1

公开(公告)日：2021-04-14

申请号：EP19806616.9

申请日：2019-05-24

申请人： Chia Tai Tianqing Pharmaceutical Group Co., Ltd. ,  Medshine Discovery Inc.

发明人： HE, Haiying ,  XIA, Jianhua ,  GONG, Zhen ,  LI, Jian ,  CHEN, Shuhui

IPC分类号： C07D487/04 ,  C07D471/04 ,  A61K31/407 ,  A61K31/437 ,  A61K31/4468 ,  A61K31/44 ,  A61K31/20

摘要： The present application relates to a 2,3-dihydro-1 H -pyrrolizine-7-formamide derivative as a nucleoprotein inhibitor and a use in preparation of a drug for treating HBV related diseases. The present application specifically relates to a compound represented by formula (II), and isomers or pharmaceutically acceptable salts thereof.