公开(公告)号：EP3865483A1

公开(公告)日：2021-08-18

申请号：EP19870704.4

申请日：2019-10-12

申请人： Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

发明人： XU, Hongjiang ,  ZHANG, Mincheng ,  ZHANG, Ying ,  SONG, Wei ,  YANG, Ling ,  ZHANG, Xiquan

IPC分类号： C07D487/04 ,  A61P35/00 ,  A61K31/519

摘要： Disclosed are a compound of formula I as a toll-like receptor 7 (TLR7) agonist or a pharmaceutically acceptable salt thereof for treating colorectal cancer, a pharmaceutical combination for treating colorectal cancer comprising the TLR7 agonist and a tyrosine kinase inhibitor, and the use of the compound of formula I or the pharmaceutically acceptable salt thereof and the pharmaceutical combination for treating colorectal cancer.

公开(公告)号：EP3816166A1

公开(公告)日：2021-05-05

申请号：EP19807809.9

申请日：2019-05-24

申请人： Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

发明人： ZHANG, Xiquan ,  YANG, Ling ,  ZHANG, Ying ,  ZHANG, Mincheng ,  SONG, Wei ,  XU, Hongjiang

IPC分类号： C07D487/04 ,  C07D519/00 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/551 ,  A61P35/00

摘要： The present application relates to a compound of formula I as a toll-Like receptor 7 (TLR7) agonist or a pharmaceutically acceptable salt thereof for treating lung cancer, a pharmaceutical combination of the TLR7 agonist and a tyrosine kinase inhibitor for treating lung cancer, and the use of the compound of formula I or the pharmaceutically acceptable salt thereof and the pharmaceutical combination for treating lung cancer.