公开(公告)号：EP3345481A1

公开(公告)日：2018-07-11

申请号：EP18156791.8

申请日：2012-08-10

申请人： Chiesi Farmaceutici S.p.a.

发明人： CHEN, Lisa Ruderman ,  SKERJANEC, Simona ,  PRATS, Jayne ,  TODD, Meredith ,  BELL, Dawn

IPC分类号： A01N43/04 ,  A61K31/7076 ,  A61K31/4365 ,  A61P7/02

CPC分类号： A61K31/7076 ,  A61K31/00 ,  A61K31/4365 ,  A61K2300/00

摘要： There is provided a reversible short-acting P2Y 12 inhibitor for use in a method of maintaining or reducing platelet activity in a subject undergoing an invasive procedure, wherein the reversible short-acting P2Y 12 inhibitor is cangrelor, wherein the administration of cangrelor is sufficient to reduce or maintain at least 60% platelet inhibition or PRU values less than 240 prior to the patient undergoing an invasive procedure.