公开(公告)号：EP3360562A1

公开(公告)日：2018-08-15

申请号：EP16853897.3

申请日：2016-10-06

申请人： Choi, Bong Keun ,  Okinawa Research Center Co. Ltd.

发明人： WOO, Je Tae

IPC分类号： A61K36/575 ,  A61K31/36 ,  A61K31/34 ,  A61K8/97 ,  A61K8/49 ,  A23L33/105 ,  A23L33/10 ,  A61Q11/00

CPC分类号： A61K36/575 ,  A23L33/10 ,  A23L33/105 ,  A23V2002/00 ,  A61K8/0216 ,  A61K8/49 ,  A61K8/4973 ,  A61K8/97 ,  A61K8/9783 ,  A61K8/9789 ,  A61K9/0053 ,  A61K9/0056 ,  A61K9/2009 ,  A61K9/2013 ,  A61K9/2018 ,  A61K9/2027 ,  A61K9/2059 ,  A61K31/34 ,  A61K31/341 ,  A61K31/36 ,  A61K2236/331 ,  A61K2236/333 ,  A61K2236/35 ,  A61K2236/39 ,  A61K2236/53 ,  A61K2800/92 ,  A61P1/02 ,  A61Q11/00

摘要： The present invention relates to a pharmaceutical composition comprising a Magnolia flower extract, a fraction thereof or the compound represented by formula 1 or formula 2 below as an active ingredient. Particularly, fargesin isolated from the said Magnolia flower extract and the fraction thereof can promote not only the growth of dental root but also the growth of periodontal tissue by forming alveolar bone in around teeth to inhibit periodontitis. Therefore, not only the fargesin but also the Magnolia flower extract comprising fargesin and the fraction thereof can be effectively used as an active ingredient for a pharmaceutical composition for promoting the growth of dental root and periodontal tissue and for preventing and treating periodontitis.