公开(公告)号：EP2333061A1

公开(公告)日：2011-06-15

申请号：EP10184533.7

申请日：2002-07-05

申请人： Commonwealth Scientific and Industrial Research Organization

发明人： Whyard, Steven ,  Cameron, Fiona Helen ,  Moghaddam, Minoo ,  Lockett, Trevor, J.

IPC分类号： C12N15/11 ,  A01K67/033

CPC分类号： C12N15/113 ,  A01K67/0337 ,  A01K2217/05 ,  A01N57/16 ,  A61K31/713 ,  A61K38/00 ,  C12N15/111 ,  C12N15/1137 ,  C12N2310/14 ,  C12N2320/32 ,  C12N2320/50 ,  C12Y302/01031

摘要： The invention is to methods of gene silencing in arthropods using dsRNA. The method is include contacting the arthropod with, and/or directly feeding the arthropod, the dsRNA to the arthropods to deliver the dsRNA to arthropod tissues. It is envisaged that the methods of the invention will have use in determining the biological function of genes in arthropods. Methods of pest control of arthropods, and of protecting arthropods against parasites and predators are provided. Transgenic arthropods expressing dsRNA molecules are also provided by the present invention.

摘要翻译： 本发明是利用dsRNA在节肢动物中进行基因沉默的方法。 该方法包括将节肢动物与节肢动物接触和/或直接喂食节肢动物dsRNA至节肢动物以将dsRNA递送至节肢动物组织。 设想本发明的方法将用于确定节肢动物中基因的生物学功能。 提供了节肢动物害虫防治方法，以及保护节肢动物对寄生虫和捕食者的防治方法。 表达dsRNA分子的转基因节肢动物也由本发明提供。