公开(公告)号：EP3291800A1

公开(公告)日：2018-03-14

申请号：EP16789996.2

申请日：2016-05-04

申请人： Confluence Pharmaceuticals, LLC

发明人： JOHNS, Steven, L. ,  PAYIE, Kenneth, G. ,  DONIPARTHI, Badrinath, R. ,  MUNIANJANAPPA, Shivaraj, B.

IPC分类号： A61K31/185 ,  A61K31/197 ,  A61K47/38 ,  A61P25/28 ,  A61P25/32

CPC分类号： A61K31/185 ,  A61K9/0056 ,  A61K9/5026 ,  A61K9/5047 ,  A61K9/5073

摘要： The present invention provides an orally-administrable, pharmaceutical formulation comprising: a plurality of pellets, wherein: the pellets comprise a core, a sustained release coating, and an enteric coating; and the core comprises an active ingredient and a diluent.

公开(公告)号：EP3331518A1

公开(公告)日：2018-06-13

申请号：EP16833870.5

申请日：2016-08-04

申请人： Confluence Pharmaceuticals, LLC

发明人： JOHNS, Steven, L. ,  ERICKSON, Craig, A.

IPC分类号： A61K31/185 ,  A61K31/42 ,  A61P25/00

CPC分类号： A61K31/185 ,  A61K9/0053 ,  A61K31/42 ,  A61K2300/00 ,  A61P25/28

摘要： Described herein is a method for treating a medical condition in a patient, the method comprising: administering to a patient in need (thereof a pharmaceutical composition comprising a therapeutically effective amount of (i) a first therapeutic agent which is acamprosate or a pharmaceutically acceptable salt thereof and (ii) a second therapeutic agent which is D-cycloserine, a salt of D-cycloserine, an ester of D-cycloserine, an alkylated D-cycloserine, or a precursor of D-cycloserine.