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公开(公告)号：EP4148143A1
公开(公告)日：2023-03-15
申请号：EP21382818.9
申请日：2021-09-13
申请人： Consejo Superior De Investigaciones Científicas (CSIC) , Universitat de Barcelona , Consorcio Centro de Investigación Biomédica en Red M.P.
发明人： MARTÍNEZ DE LA FUENTE, Jesús , CUESTAS AYLLÓN, Carlos , GRAZÚ BONAVÍA, María Valeria , FERNÁNDEZ SÁNCHEZ, César , GUTIÉRREZ CAPITÁN, Manuel , BALDI COLL, Antonio , ERITJA CASADELLÀ, Ramon , MARCO COLÁS, María Pilar , VILAPLANA HOLGADO, María Luisa , AVIÑÓ ANDRÉS, Ana María , CIUDAD GÓMEZ, Carlos Julián , NOÉ MATA, Verónica
IPC分类号： C12Q1/6816 , C12Q1/70
摘要： The present invention relates to an in vitro method for detecting at least one target polynucleotide in a test sample, wherein the method comprises the steps of contacting the test sample with a first oligonucleotide and a second oligonucleotide and detecting the hybridization between the first and the second oligonucleotides to the at least one target polynucleotide. The present invention also relates to devices or systems to implement the method, and kits of parts comprising said oligonucleotides.
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公开(公告)号：EP4402282A1
公开(公告)日：2024-07-24
申请号：EP22789499.5
申请日：2022-09-13
申请人： Consejo Superior De Investigaciones Científicas (CSIC) , Universitat de Barcelona , Consorcio Centro de Investigación Biomédica en Red
发明人： MARTÍNEZ DE LA FUENTE, Jesús , CUESTAS AYLLÓN, Carlos , GRAZÚ BONAVÍA, María Valeria , FERNÁNDEZ SÁNCHEZ, César , GUTIÉRREZ CAPITÁN, Manuel , BALDI COLL, Antonio , ERITJA CASADELLÀ, Ramon , MARCO COLÁS, María Pilar , VILAPLANA HOLGADO, María Luisa , AVIÑÓ ANDRÉS, Ana María , CIUDAD GÓMEZ, Carlos Julián , NOÉ MATA, Verónica
IPC分类号： C12Q1/6816 , C12Q1/70
CPC分类号： C12Q1/6816 , C12Q1/70
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公开(公告)号：EP4189375A1
公开(公告)日：2023-06-07
申请号：EP21746501.2
申请日：2021-07-29
IPC分类号： G01N27/27 , B01L3/00 , G01N33/49 , G01N33/543
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公开(公告)号：EP3951374A1
公开(公告)日：2022-02-09
申请号：EP20382721.7
申请日：2020-08-03
IPC分类号： G01N27/27 , B01L3/00 , G01N33/49 , G01N33/543
摘要： The invention refers to a biosensor system for quick and multiplexed detection of biomarkers present in biological fluids. The biosensor system comprises a reusable array of at least two individual electrochemical cells (1a,1b,1c,1d,1e) coupled to a disposable fluidic component. Each cell can be addressed individually. The array includes a set of working electrodes (2a,2b,2c,2d) and at least one shared counter/reference electrode (5) in common for all the electrochemical cells, such that each electrochemical cell includes one working electrode and the shared counter/reference electrode. Preferably, the system includes a disposable paper component (8) having a reactive microfluidic component distributed in fluidic channels (9), isolated by hydrophobic barriers (10). The paper component (8) is operatively aligned with the array of electrochemical cells for the electrochemical detection by means of a polymeric cartridge. The multiplexed biosensor system features a reduced size, and that allows reduction of analysis costs and material waste.
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