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1.发明授权CYCLIC PEPTIDES BINDING CXCR4 RECEPTOR AND RELATIVE MEDICAL AND DIAGNOSTIC USES 有权CYCLIC肽与CXCR4受体的结合以及相关的医学和诊断用途
公开(公告)号：EP2528936B1
公开(公告)日：2014-10-22
申请号：EP11710271.5
申请日：2011-01-20
申请人： Consiglio Nazionale Delle Ricerche , IRCCS- Istituto Nazionale Per Lo Studio E La Cura Dei Tumori "Fondazione Giovanni Pascale"
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2.发明授权CYCLIC PEPTIDES BINDING CXCR4 RECEPTOR AND RELATIVE MEDICAL AND DIAGNOSTIC USES 有权骑自行车，CXCR4受体结合肽和相关的中位数和诊断用途
公开(公告)号：EP2528936B9
公开(公告)日：2014-12-31
申请号：EP11710271.5
申请日：2011-01-20
申请人： Consiglio Nazionale Delle Ricerche , IRCCS- Istituto Nazionale Per Lo Studio E La Cura Dei Tumori "Fondazione Giovanni Pascale"
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3.发明公开CYCLIC PEPTIDES BINDING CXCR4 RECEPTOR AND RELATIVE MEDICAL AND DIAGNOSTIC USES 有权骑自行车，CXCR4受体结合肽和相关的中位数和诊断用途
公开(公告)号：EP2528936A1
公开(公告)日：2012-12-05
申请号：EP11710271.5
申请日：2011-01-20
申请人： Consiglio Nazionale Delle Ricerche , IRCCS- Istituto Nazionale Per Lo Studio E La Cura Dei Tumori "Fondazione Giovanni Pascale"
发明人： AMODEO, Pietro , VITALE, Rosamaria , DE LUCA, Stefania , SCALA, Stefania , CASTELLO, Giuseppe , SIANI, Alfredo
IPC分类号： C07K7/06
摘要： The present invention relates to the identification of new peptides and peptidomimetics which bind the CXCR4 receptor, capable of forming complexes with receptors for chemokines, in particular with CXCR4. The invention also relates to the use of these peptides for the treatment, prevention and diagnosis of diseases which involve chemokine receptors (i.e. neoplasias, metastases, HIV-I virus infections), and also the mobilization of stem cells of hemopoietic precursors in the case of autologous transplants. Finally, the invention comprises pharmaceutical compositions and diagnostic kits comprising said peptides.
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