公开(公告)号：EP2771298B1

公开(公告)日：2017-12-13

申请号：EP12787984.9

申请日：2012-10-25

申请人： Corning Incorporated

发明人： WEEKS, Wendell, P. ,  SCHAUT, Robert, Anthony ,  DEMARTINO, Steven,Edward ,  PEANASKY, John, Stephen

IPC分类号： C03C3/087 ,  C03C3/091 ,  C03C21/00

CPC分类号： A61J1/1468 ,  A61J1/00 ,  A61J1/065 ,  A61K31/403 ,  A61K38/17 ,  A61K38/1816 ,  A61K38/193 ,  A61K38/28 ,  A61K39/3955 ,  C03C3/087 ,  C03C3/091 ,  C03C4/20 ,  C03C21/002 ,  C07K16/241 ,  Y02A50/463 ,  Y02A50/465 ,  Y10T428/131

摘要： The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, HUMIRA (Adalimumab).

公开(公告)号：EP2819965A2

公开(公告)日：2015-01-07

申请号：EP13708623.7

申请日：2013-02-27

申请人： Corning Incorporated

发明人： GOMEZ, Sinue ,  KICZENSKI, Timothy, J ,  MAURO, John, Christopher ,  SCHAUT, Robert, Anthony ,  SMEDSKJAER, Morten, Mattrup ,  VENKATARAMAN, Natesan

IPC分类号： C03C21/00 ,  C03C17/02

CPC分类号： C03C3/093 ,  B32B17/00 ,  B32B2307/308 ,  B32B2307/558 ,  C03B17/02 ,  C03C3/091 ,  C03C4/18 ,  C03C21/002 ,  C03C2204/00 ,  Y02P40/57 ,  Y10T428/24942

摘要： Glass compositions and glass articles comprising the glass compositions are disclosed. In one embodiment, a glass composition includes from about 65 mol. % to about 70 mol. % SiO2; from about 9 mol. % to about 14 mol. % Al2O3; and from about 0 mol. % to about 11 mol. % B2O3 as glass network formers. The glass composition also includes from about 5 mol. % to less than 10 mol. % alkali oxide R2O, wherein R is at least one of Li, Na, and K. The glass composition also includes from about 3 mol. % to about 11 mol. % of divalent oxide MO, wherein M is at least one of Mg, Ca, Ba, SrO and Zn. The glass composition has a coefficient of thermal expansion which is less than or equal to 55×10-7/° C. and is amenable to strengthening by ion-exchange. The glass composition is well suited for use as the glass cladding layers of a laminated glass article.

公开(公告)号：EP2925697A1

公开(公告)日：2015-10-07

申请号：EP13814278.1

申请日：2013-11-22

申请人： Corning Incorporated

发明人： CHANG, Theresa ,  DANIELSON, Paul, Stephen ,  DEMARTINO, Steven, Edward ,  FADEEV, Andrei, Gennadyevich ,  MORENA, Robert, Michael ,  PAL, Santona ,  PEANASKY, John, Stephen ,  SCHAUT, Robert, Anthony ,  VENKATARAMAN, Natesan ,  VERKLEEREN, Ronald, Luce

IPC分类号： C03C17/00 ,  C03C17/30 ,  C03C17/32 ,  C03C17/42 ,  C03C21/00 ,  B32B17/06 ,  B65D25/14 ,  C09D179/08 ,  B65D1/40

CPC分类号： C03C17/42 ,  A61J1/1468 ,  B32B17/06 ,  B65D1/0207 ,  B65D1/0215 ,  B65D1/40 ,  B65D23/02 ,  B65D23/0814 ,  B65D23/0821 ,  B65D25/14 ,  B65D25/34 ,  B65D65/42 ,  C03C15/02 ,  C03C17/00 ,  C03C17/005 ,  C03C17/30 ,  C03C17/32 ,  C03C17/3405 ,  C03C21/002 ,  C03C2217/78 ,  C03C2218/111 ,  C09D179/08 ,  Y10T428/13 ,  Y10T428/131 ,  Y10T428/1317 ,  Y10T428/315

摘要： The glass containers described herein have at least two performance attributes selected from resistance to delamination, improved strength, and increased damage resistance. In one embodiment, a glass container with resistance to delamination and improved strength may include a body having an inner surface, an outer surface and a wall thickness extending between the outer surface and the inner surface. At least the inner surface of the body may have a delamination factor less than or equal to 10. The glass container may further include a compressively stressed layer extending from the outer surface of the body into the wall thickness. The compressively stressed layer may have a surface compressive stress greater than or equal to 150 MPa.

摘要翻译： 根据一个实施方案，涂覆的玻璃包装可以包括根据USP 660具有1型化学耐久性的玻璃体，根据ISO 695的A2级耐碱性或更好的，以及根据ISO 719的更高的HGB2型耐水解性。 玻璃体可以包括内表面和外表面。 厚度≤100微米的润滑涂层可以位于外表面上。 具有涂层的外表面的部分可以具有比未涂覆的玻璃包装小至少20％的摩擦系数，并且经过去热原后摩擦系数不会增加大于30％。 涂层玻璃包装的水平压缩强度比未涂覆的玻璃包装大至少10％，并且在去热原后水平压缩强度不降低20％以上。

公开(公告)号：EP2925694A1

公开(公告)日：2015-10-07

申请号：EP13812242.9

申请日：2013-11-22

申请人： Corning Incorporated

发明人： CHANG, Theresa ,  DANIELSON, Paul, Stephen ,  DEMARTINO, Steven, Edward ,  FADEEV, Andrei, Gennadyevich ,  MORENA, Robert, Michael ,  PAL, Santona ,  PEANASKY, John, Stephen ,  SCHAUT, Robert, Anthony ,  VENKATARAMAN, Natesan ,  VERKLEEREN, Ronald, Luce ,  TIMMONS, Christopher, Lee

IPC分类号： C03C17/00 ,  C03C17/30 ,  C03C17/32 ,  C03C17/42 ,  C03C21/00 ,  B32B17/06 ,  B65D25/14 ,  C09D179/08 ,  B65D23/08 ,  B65D1/40

CPC分类号： C03C17/42 ,  A61J1/1468 ,  B32B17/06 ,  B65D1/0207 ,  B65D1/0215 ,  B65D1/40 ,  B65D23/02 ,  B65D23/0814 ,  B65D23/0821 ,  B65D25/14 ,  B65D25/34 ,  B65D65/42 ,  C03C15/02 ,  C03C17/00 ,  C03C17/005 ,  C03C17/30 ,  C03C17/32 ,  C03C17/3405 ,  C03C21/002 ,  C03C2217/78 ,  C03C2218/111 ,  C09D179/08 ,  Y10T428/13 ,  Y10T428/131 ,  Y10T428/1317 ,  Y10T428/315

摘要： According to one embodiment, a coated glass package may include a glass body having a Type 1 chemical durability according to USP 660, a class A2 base resistance or better according to ISO 695, and a type HGB2 hydrolytic resistance or better according to ISO 719. The glass body may include an interior surface and an exterior surface. A lubricous coating having a thickness of ≦100 microns may be positioned on the exterior surface. The portion of the exterior surface with the coating may have a coefficient of friction that is at least 20% less than an uncoated glass package and the coefficient of friction does not increase by more than 30% after undergoing depyrogenation. A horizontal compression strength of the coated glass package is at least 10% greater than an uncoated glass package and the horizontal compression strength is not reduced by more than 20% after depyrogenation.

摘要翻译： 根据一个实施方案，涂覆的玻璃包装可以包括根据USP 660具有1型化学耐久性的玻璃体，根据ISO 695的A2级耐碱性或更好的，以及根据ISO 719的更高的HGB2型耐水解性。 玻璃体可以包括内表面和外表面。 厚度≤100微米的润滑涂层可以位于外表面上。 具有涂层的外表面的部分可以具有比未涂覆的玻璃包装小至少20％的摩擦系数，并且经过去热原后摩擦系数不会增加大于30％。 涂层玻璃包装的水平压缩强度比未涂覆的玻璃包装大至少10％，并且在去热原后水平压缩强度不降低20％以上。

公开(公告)号：EP2771295A1

公开(公告)日：2014-09-03

申请号：EP12787250.5

申请日：2012-10-25

申请人： Corning Incorporated

发明人： WEEKS, Wendell, P. ,  SCHAUT, Robert, Anthony ,  DEMARTINO, Steven, Edward ,  PEANASKY, John, Stephen

IPC分类号： C03C3/087 ,  C03C3/091 ,  C03C21/00

CPC分类号： A61J1/1468 ,  A61J1/00 ,  A61J1/065 ,  A61K31/403 ,  A61K38/17 ,  A61K38/1816 ,  A61K38/193 ,  A61K38/28 ,  A61K39/3955 ,  C03C3/087 ,  C03C3/091 ,  C03C4/20 ,  C03C21/002 ,  C07K16/241 ,  Y02A50/463 ,  Y02A50/465 ,  Y10T428/131

摘要： The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, HUMIRA (Adalimumab).

摘要翻译： 本发明至少部分基于对至少部分由玻璃组合物形成的药物容器的鉴定，所述玻璃组合物表现出降低的分层倾向，即降低了脱落玻璃微粒的倾向。 结果，目前要求保护的容器特别适用于储存药物组合物，特别是包含药物活性成分的药物溶液。

公开(公告)号：EP2819965B1

公开(公告)日：2018-09-19

申请号：EP13708623.7

申请日：2013-02-27

申请人： Corning Incorporated

发明人： GOMEZ, Sinue ,  KICZENSKI, Timothy, J ,  MAURO, John, Christopher ,  SCHAUT, Robert, Anthony ,  SMEDSKJAER, Morten, Mattrup ,  VENKATARAMAN, Natesan

IPC分类号： C03C21/00 ,  C03C17/02

CPC分类号： C03C3/093 ,  B32B17/00 ,  B32B2307/308 ,  B32B2307/558 ,  C03B17/02 ,  C03C3/091 ,  C03C4/18 ,  C03C21/002 ,  C03C2204/00 ,  Y02P40/57 ,  Y10T428/24942

摘要： Glass compositions and glass articles comprising the glass compositions are disclosed. In one embodiment, a glass composition includes from about 65 mol. % to about 70 mol. % SiO2; from about 9 mol. % to about 14 mol. % Al2O3; and from about 0 mol. % to about 11 mol. % B2O3 as glass network formers. The glass composition also includes from about 5 mol. % to less than 10 mol. % alkali oxide R2O, wherein R is at least one of Li, Na, and K. The glass composition also includes from about 3 mol. % to about 11 mol. % of divalent oxide MO, wherein M is at least one of Mg, Ca, Ba, SrO and Zn. The glass composition has a coefficient of thermal expansion which is less than or equal to 55×10-7/° C. and is amenable to strengthening by ion-exchange. The glass composition is well suited for use as the glass cladding layers of a laminated glass article.

公开(公告)号：EP2771301B1

公开(公告)日：2017-12-20

申请号：EP12795117.6

申请日：2012-10-25

申请人： Corning Incorporated

发明人： WEEKS, Wendell, P. ,  SCHAUT, Robert, Anthony ,  DEMARTINO, Steven, Edward ,  PEANASKY, John, Stephen

IPC分类号： C03C3/087 ,  C03C3/091 ,  C03C21/00

CPC分类号： A61J1/1468 ,  A61J1/00 ,  A61J1/065 ,  A61K31/403 ,  A61K38/17 ,  A61K38/1816 ,  A61K38/193 ,  A61K38/28 ,  A61K39/3955 ,  C03C3/087 ,  C03C3/091 ,  C03C4/20 ,  C03C21/002 ,  C07K16/241 ,  Y02A50/463 ,  Y02A50/465 ,  Y10T428/131

摘要： The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, HUMIRA (Adalimumab).

公开(公告)号：EP2867179A1

公开(公告)日：2015-05-06

申请号：EP13735550.9

申请日：2013-06-28

申请人： Corning Incorporated

发明人： ADIB, Kaveh ,  BOOKBINDER, Dana, Craig ,  CHANG, Theresa ,  DANIELSON, Paul, Stephen ,  DEMARTINO, Steven, Edward ,  DRAKE, Melinda, Ann ,  FADEEV, Andrei, Gennadyevich ,  HAMILTON, James, Patrick ,  MORENA, Robert, Michael ,  PAL, Santona ,  PEANASKY, John, Stephen ,  SAHA, Chandan, Kumar ,  SCHAUT, Robert, Anthony ,  SCHIEFELBEIN, Susan, Lee ,  TIMMONS, Christopher, Lee

IPC分类号： C03C17/00 ,  C03C17/30 ,  C03C17/32 ,  C03C17/42 ,  C03C21/00 ,  B32B17/06 ,  B65D25/14 ,  C09D179/08

CPC分类号： B65D23/0814 ,  A61J1/1468 ,  B32B17/06 ,  B65D1/40 ,  B65D25/14 ,  C03C3/087 ,  C03C17/005 ,  C03C17/30 ,  C03C17/32 ,  C03C17/3405 ,  C03C17/42 ,  C03C21/002 ,  C03C2217/78 ,  C03C2218/111 ,  C08G73/105 ,  C08G73/1071 ,  C09D179/08 ,  C08K5/544

摘要： Delamination resistant glass containers with heat-tolerant coatings are disclosed. In one embodiment, a glass container may include a glass body having an interior surface, an exterior surface and a wall thickness extending from the exterior surface to the interior surface. At least the interior surface of the glass body is delamination resistant. The glass container may further include a heat-tolerant coating positioned on at least a portion of the exterior surface of the glass body. The heat-tolerant coating may be thermally stable at temperatures greater than or equal to 260° C. for 30 minutes.

公开(公告)号：EP2771298A1

公开(公告)日：2014-09-03

申请号：EP12787984.9

申请日：2012-10-25

申请人： Corning Incorporated

发明人： WEEKS, Wendell, P. ,  SCHAUT, Robert, Anthony ,  DEMARTINO, Steven,Edward ,  PEANASKY, John, Stephen

IPC分类号： C03C3/087 ,  C03C3/091 ,  C03C21/00

CPC分类号： A61J1/1468 ,  A61J1/00 ,  A61J1/065 ,  A61K31/403 ,  A61K38/17 ,  A61K38/1816 ,  A61K38/193 ,  A61K38/28 ,  A61K39/3955 ,  C03C3/087 ,  C03C3/091 ,  C03C4/20 ,  C03C21/002 ,  C07K16/241 ,  Y02A50/463 ,  Y02A50/465 ,  Y10T428/131

摘要： The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, HUMIRA (Adalimumab).

摘要翻译： 本发明至少部分基于对至少部分由玻璃组合物形成的药物容器的鉴定，所述玻璃组合物表现出降低的分层倾向，即降低了脱落玻璃微粒的倾向。 结果，本发明要求保护的容器特别适用于药物组合物的储存，特别是包含药物活性成分，例如RITUXAN（利妥昔单抗），阿瓦斯汀（贝伐单抗），LUCENTIS（Ranibizumab）或赫赛汀（曲妥珠单抗 ）。

公开(公告)号：EP2771297A1

公开(公告)日：2014-09-03

申请号：EP12787983.1

申请日：2012-10-25

申请人： Corning Incorporated

发明人： WEEKS, Wendell, P. ,  SCHAUT, Robert, Anthony ,  DEMARTINO, Steven, Edward ,  PEANASKY, John, Stephen

IPC分类号： C03C3/087 ,  C03C3/091 ,  C03C21/00

CPC分类号： A61J1/1468 ,  A61J1/00 ,  A61J1/065 ,  A61K31/403 ,  A61K38/17 ,  A61K38/1816 ,  A61K38/193 ,  A61K38/28 ,  A61K39/3955 ,  C03C3/087 ,  C03C3/091 ,  C03C4/20 ,  C03C21/002 ,  C07K16/241 ,  Y02A50/463 ,  Y02A50/465 ,  Y10T428/131

摘要： The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, HUMIRA (Adalimumab).

摘要翻译： 本发明至少部分地基于鉴定至少部分由玻璃组合物形成的药物容器，所述玻璃组合物显示降低的分层倾向，即降低玻璃微粒的倾向。 因此，目前要求保护的容器特别适用于药物组合物的储存，特别是适用于包含药物活性成分例如HUMIRA（阿达木单抗）的药物溶液。