公开(公告)号：EP1166120B1

公开(公告)日：2004-08-04

申请号：EP00917985.4

申请日：2000-03-15

申请人： Coulter International Corp.

发明人： SIIMAN, Olavi ,  MATIJEVIC, Egon ,  SONDI, Ivan

IPC分类号： G01N33/58 ,  G01N33/533 ,  G01N33/543

CPC分类号： B82Y15/00 ,  G01N33/588 ,  Y10T428/2982 ,  Y10T428/2991

公开(公告)号：EP1166120A1

公开(公告)日：2002-01-02

申请号：EP00917985.4

申请日：2000-03-15

申请人： Coulter International Corp.

发明人： SIIMAN, Olavi ,  MATIJEVIC, Egon ,  SONDI, Ivan

IPC分类号： G01N33/58 ,  G01N33/533 ,  G01N33/543

CPC分类号： B82Y15/00 ,  G01N33/588 ,  Y10T428/2982 ,  Y10T428/2991

摘要： A semiconductor nanoparticle for use in analysis of biological samples is described. This semiconductor nanoparticle is composed of an aminodextran which is bound to at least one nanoparticle of the formula (X Y)n wherein X is selected from the group comprising Cd?2+, Hg2+¿, and Zn2+ and combinations thereof; and Y is selected from the group comprising S?2-, Se2- and Te2-¿ and combinations thereof; and n = approximately 50 to 1000. Also provided are methods of making these semiconductor nanoparticles and methods of making conjugates composed of these semiconductor nanoparticles linked to ligands. Also described are uses for the conjugates in a variety of biological assays.