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1.发明公开EXTRACT OF PIPER BETEL LEAVES FOR THE TREATMENT OF HUMAN MALIGNANCIES BY INDUCING OXIDATIVE STRESS 有权PIPER槟榔树叶提取物用于人类疾病的治疗诱导氧化应激
公开(公告)号：EP2224938A1
公开(公告)日：2010-09-08
申请号：EP08861477.1
申请日：2008-12-02
发明人： BANDYOPADHYAY, Santu , PAL, Bikas, Chandra , CHAKRABORTY, Jayashree, Bagchi , RAKSHIT, Srabanti , MANDAL, Labanya , PAUL, Kausik , BISWAS, Nabendu , MANNA, Anirban
CPC分类号： A61K36/67
摘要： This invention relates to method of treating human malignancies of different origin that are sensitive to oxidative stress by administering effective amount of extract of Piper betel leaves along with a pharmaceutically acceptable additives
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2.发明授权EXTRACT OF PIPER BETEL LEAVES FOR THE TREATMENT OF HUMAN MALIGNANCIES BY INDUCING OXIDATIVE STRESS 有权PIPER槟榔树叶提取物用于人类疾病的治疗诱导氧化应激
公开(公告)号：EP2224938B1
公开(公告)日：2016-07-27
申请号：EP08861477.1
申请日：2008-12-02
发明人： BANDYOPADHYAY, Santu , PAL, Bikas, Chandra , CHAKRABORTY, Jayashree, Bagchi , RAKSHIT, Srabanti , MANDAL, Labanya , PAUL, Kausik , BISWAS, Nabendu , MANNA, Anirban
CPC分类号： A61K36/67
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3.发明授权INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE (PI3) AND INDUCERS OF NITRIC OXIDE (NO) 有权抑制剂磷脂酰肌醇3-激酶（PI3）和一氧化氮（NO）INDUCTORS
公开(公告)号：EP2385934B1
公开(公告)日：2016-05-18
申请号：EP10703198.1
申请日：2010-01-12
发明人： BANDYOPADHYAY, Santu , PAL, Bikas, Chandra , PARASURAMAN, Jaisankar , ROY, Siddhartha , CHAKRABOTRY, Jayashree, Bagchi , MUKHERJEE, Indrani, Choudhury , MAHATO, Sanjit, Kumar , KONAR, Aditya , RAKSHIT, Srabanti , MANDAL, Labanya , GANGULY, Dipyaman , PAUL, Kausik , MANNA, Anirban , VINAYAGAM, Jayaraman , PAL, Churala
IPC分类号： C07C39/19 , C07D317/06 , C07C255/00 , A61K31/36 , A61P35/00
CPC分类号： C07D317/06 , C07C251/40 , C07C251/66 , C07C255/36 , C07C255/38
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4.发明公开INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE (PI3) AND INDUCERS OF NITRIC OXIDE (NO) 有权抑制剂磷脂酰肌醇3-激酶（PI3）和一氧化氮（NO）INDUCTORS
公开(公告)号：EP2385934A1
公开(公告)日：2011-11-16
申请号：EP10703198.1
申请日：2010-01-12
发明人： BANDYOPADHYAY, Santu , PAL, Bikas, Chandra , PARASURAMAN, Jaisankar , ROY, Siddhartha , CHAKRABOTRY, Jayashree, Bagchi , MUKHERJEE, Indrani, Choudhury , MAHATO, Sanjit, Kumar , KONAR, Aditya , RAKSHIT, Srabanti , MANDAL, Labanya , GANGULY, Dipyaman , PAUL, Kausik , MANNA, Anirban , VINAYAGAM, Jayaraman , PAL, Churala
IPC分类号： C07C39/19 , C07D317/06 , C07C255/00 , A61K31/36 , A61P35/00
CPC分类号： C07D317/06 , C07C251/40 , C07C251/66 , C07C255/36 , C07C255/38
摘要： The present invention relates to compounds of general formula 1 for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention also relates to the use of compound of general formula 1 for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention further relates to a method of treating malignancy by inhibition of PI3-Akt pathway and or induction of NO by administration of compound or said composition to a mammal in need thereof.
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