公开(公告)号：EP1802336B1

公开(公告)日：2011-09-07

申请号：EP05808091.2

申请日：2005-10-13

申请人： Crucell Holland B.V. ,  GlaxoSmithKline Biologicals SA ,  The Government of the United States, as represen- ted by the Secretary of the Army, on behalf of the Walter Reed Army Institute of Research

发明人： PAU, Maria Grazia ,  GOUDSMIT, Jaap ,  COHEN, Joseph D., GlaxoSmithKline ,  DUBOIS, Patrice M., GlaxoSmithKline ,  STEWART, V. Ann ,  HEPPNER, Donald

IPC分类号： A61K39/015

CPC分类号： A61K39/015 ,  A61K2039/5256 ,  A61K2039/55572 ,  A61K2039/55577 ,  A61K2039/6075 ,  Y02A50/412

摘要： Described are vaccine regimens in which specific prime/boost regimens are applied using low-neutralized recombinant adenoviral vectors harboring nucleic acids encoding antigens from Plasmodium falciparum and purified recombinant protein vaccines such as RTS,S, in the context of appropriate adjuvants.

公开(公告)号：EP1802336A1

公开(公告)日：2007-07-04

申请号：EP05808091.2

申请日：2005-10-13

申请人： Crucell Holland B.V. ,  GlaxoSmithKline Biologicals SA ,  The Government of the United States, as represen- ted by the Secretary of the Army, on behalf of the Walter Reed Army Institute of Research

发明人： PAU, Maria Grazia ,  GOUDSMIT, Jaap ,  COHEN, Joseph D., GlaxoSmithKline ,  DUBOIS, Patrice M., GlaxoSmithKline ,  STEWART, V. Ann ,  HEPPNER, Donald

IPC分类号： A61K39/015

CPC分类号： A61K39/015 ,  A61K2039/5256 ,  A61K2039/55572 ,  A61K2039/55577 ,  A61K2039/6075 ,  Y02A50/412

摘要： Described are vaccine regimens in which specific prime/boost regimens are applied using low-neutralized recombinant adenoviral vectors harboring nucleic acids encoding antigens from Plasmodium falciparum and purified recombinant protein vaccines such as RTS,S, in the context of appropriate adjuvants.