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公开(公告)号:EP1357847B1
公开(公告)日:2006-03-22
申请号:EP02710716.8
申请日:2002-01-25
IPC分类号: A61B18/02
CPC分类号: A61B18/02 , A61B2017/00084 , A61B2017/00199 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268
摘要: A cryogenic medical system includes a medical device and a console connectable to the medical device at a connection point. The console controls the temperature of the medical device. The console includes a first cooling system directing coolant to the medical device at a first temperature along a coolant supply line and a second cooling system chilling the coolant within the coolant supply line to a temperature below the first temperature before the coolant reaches the connection point.
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公开(公告)号:EP1424950A2
公开(公告)日:2004-06-09
申请号:EP02766182.6
申请日:2002-08-29
发明人: LANE, Miriam , CAPUANO, Leonilda , HOLTAN, David , LALONDE, Jean-Pierre , LÜCKGE, Claudia , PAEGARD, Jean-Luc , ABBOUD, Marwan , ALASMAR, Johny , BENRABAH, Abderrahim , CHEN, Ken , LEHMANN, John, W. , MARCHAND, Philippe , MARTIN, Robert , MILDER, Frederic, L. , NAHON, Daniel
IPC分类号: A61B18/18
CPC分类号: A61B18/02 , A61B2017/22001 , A61B2017/22051 , A61B2017/22054 , A61B2017/22069 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268
摘要: An elongated catheter device with a distal balloon assembly is adapted for endovascular insertion. Coolant injected through the device may directly cool tissue contacting the balloon (212), or may cool a separate internal chamber. In the first case, the coolant also inflates the balloon, and spent coolant is returned to the handle via a return passage extending through the body of the catheter.Plural balloons may be provided, wherein a secondary outer balloon (212) surrounds a primary inner balloon (203), the primary balloon being filled with coolant and acting as the cooling chamber. The secondary balloon is coupled to a vacuum return lumen (205) to serve as a robust leak containment device and thermal insulator around the cooling chamber.
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公开(公告)号:EP1357847A1
公开(公告)日:2003-11-05
申请号:EP02710716.8
申请日:2002-01-25
IPC分类号: A61B18/02
CPC分类号: A61B18/02 , A61B2017/00084 , A61B2017/00199 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268
摘要: A cryogenic medical system includes a medical device and a console connectable to the medical device at a connection point. The console controls the temperature of the medical device. The console includes a first cooling system directing coolant to the medical device at a first temperature along a coolant supply line and a second cooling system chilling the coolant within the coolant supply line to a temperature below the first temperature before the coolant reaches the connection point.
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公开(公告)号:EP1148833A1
公开(公告)日:2001-10-31
申请号:EP00901435.8
申请日:2000-01-25
IPC分类号: A61B18/02
CPC分类号: A61B18/02 , A61B2017/00092 , A61B2017/00119 , A61B2018/0212 , A61B2018/0262 , A61F7/12
摘要: A surgical device includes a device body defining a sealed fluid path having a first end and a second end, a refrigerant supply in communication with the first end of the sealed fluid path, and a vacuum source in communication with the second end of the sealed fluid path. Leak detection apparatus can be provided in communication with the sealed fluid path.
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公开(公告)号:EP1494603B1
公开(公告)日:2009-02-11
申请号:EP03743964.3
申请日:2003-03-10
发明人: LALONDE, Jean-Pierre
IPC分类号: A61B18/02
CPC分类号: A61M25/0029 , A61B5/042 , A61B18/02 , A61B2017/00243 , A61B2017/00292 , A61B2017/00973 , A61B2017/22051 , A61B2018/00095 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61F2007/0298 , A61M2025/0037 , A61M2025/0039 , Y10S977/906
摘要: A cryogenic catheter includes an outer flexible member having at least one cryogenic fluid path through the flexible member. The at least one fluid path is defined by a plurality of flexible members disposed within the outer flexible member. Such flexible members can be moved within the cryogenic catheter in order to vary the distance existing between the outer member and the flexible members.
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公开(公告)号:EP1296604A1
公开(公告)日:2003-04-02
申请号:EP00929146.9
申请日:2000-04-27
发明人: SANTOIANNI, Domenic , NAHON, Daniel , WITTENBERGER, Dan , LALONDE, Jean-Pierre , PETRE, Cristian
CPC分类号: A61B18/02 , A61B90/04 , A61B90/39 , A61B2017/00084 , A61B2017/00243 , A61B2017/003 , A61B2017/00473 , A61B2017/00477 , A61B2017/3488 , A61B2018/0212 , A61B2090/3933 , A61M25/0147 , A61M2025/0163
摘要: A catheter for ablating tissue, for example to treat a cardiac arrhythmia, includes a handle, a shapeable shaft and a distal ablation segment. The shaft retains a first position until manipulated to a further position with the application of moderate manual pressure. The shaft incorporates plastically deformable elements and is shapeable to conform to an insertion path or the particular anatomy of a patient for accessing a site to be ablated. Once shaped, the shaft retains its shape as the catheter is inserted or manipulated to the predetermined tissue treatment location and the distal segment is urged into contact with the tissue site. A deflection mechanism may be provided to facilitate navigation to, or to deflect the ablation segment into conformal contact with, the tissue target. In a further or alternative embodiment, a second or auxiliary shaft member extends distally from the ablation segment, allowing the segment to be threaded by or pulled past occluding tissue to a remote target tissue site. By gripping the end of the second shaft, the flexible ablation segment may be either tensioned or pulled inward against, or flexed and pushed outward against a treatment site, such as a region of the posterior epicardial wall, thus providing more effective contact for a broad range of dispositions and tissue orientations. In another embodiment, a thermal shield extends over a portion of the ablation segment, shielding adjacent tissue from damage while still effectively exposing the target tissue to ablation energy. The shield may be rotated or moved axially to delimit an area of cryogenic contact and achieve better protection of surrounding tissue structures in occluded or remote treatment target regions.
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公开(公告)号:EP1148832A1
公开(公告)日:2001-10-31
申请号:EP00901434.1
申请日:2000-01-25
IPC分类号: A61B18/02
CPC分类号: A61B18/02 , A61B2017/00092 , A61B2017/00119 , A61B2018/0212 , A61B2018/0262 , A61F7/12
摘要: A coolant system for a cryoablation or treatment probe such as a mapping or ablation catheter, or a treatment wand, includes a compressor and condenser having a low pressure inlet side and a high pressure outlet side, wherein the outlet side passes through a heat exchanger and is cooled by the inlet side and conditioned for injection to a catheter inlet. A vacuum return system connectable to the catheter outlet draws thermally expended coolant from the catheter and returns it to the low pressure inlet side. A motorized pressure regulator between the heat exchanger and the catheter inlet determines the pressure of coolant passing into the catheter and thus regulates the cooling rate for a selected mapping or ablation regimen. The low pressure compressor inlet supply preferentially conditions the pressurized coolant to ambient temperature or lower before injection into the catheter, allowing the coolant to travel through the body at ambient before expansion in the tip. In a preferred embodiment, a coolant reservoir feeds into the low pressure inlet side and receives a return flow of excess fluid from a branch off the outlet side of the compressor. The vacuum return assures that coolant does not leak into the blood stream, and preferably various check valves and bypass valves operate in the event of pressure build-up to return fluid to either the inlet or supply from different points along the loop. The coolant mixture preferably has a boiling point of approximately -60° Fahrenheit at about 1-2 bar, and may be compressed to several hundred psi. The entire system is amenable to microprocessor control for providing ablation cooling cycles to operate the catheter tip in accordance with a selected protocol, and for effecting system functions such as recharging and venting of the supply, and shutting down during nonuse or upon occurrence of a fault condition.
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公开(公告)号:EP1432363B1
公开(公告)日:2009-04-08
申请号:EP02767804.4
申请日:2002-09-23
IPC分类号: A61B18/02
CPC分类号: A61B18/02 , A61B2018/0212 , A61B2018/0268
摘要: The present invention provides a medical device to cold treat desired regions. An injection tube with an open distal end is disposed inside of a catheter tube, defining a return lumen therein. A supply of cryogenic fluid, regulated by a controller mechanism coupled to the device, flows through the injection tube and into the distal tip portion of the catheter tube, whereupon the fluid is returned from the catheter through the return lumen. The expansion and evaporation of cryogenic fluid inside the device serves to cool the surrounding areas external to and proximate the distal end of the device. An additional restriction tube is provided in the length of the catheter tube to regulate the pressure of the flow of cryogen therethrough so as to create higher operating pressures in the distal end of the device and thereby enhance the cooling power and temperature stability of the device at a lower range of fluid flow rates without reaching the triple point of the cryogenic fluid.
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公开(公告)号:EP1365695B1
公开(公告)日:2009-01-21
申请号:EP02748303.1
申请日:2002-02-27
发明人: LALONDE, Jean-Pierre
IPC分类号: A61B18/02
CPC分类号: A61B18/02 , A61B2018/0212 , A61B2018/0262
摘要: The present invention provides a medical device to cold treat desired regions. An injection tube with an open distal end, and at least one aperture proximate thereto is disposed inside of a cooling tube, defining a cooling lumen therebetween. A third outer tube member is disposed around the second cooling member, defining a return lumen therebetween. A supply of fluid, regulated by a controller mechanism coupled to the device, flows through the injection lumen, the apertures and the cooling lumen to insulate and cool the fluid supplied into the injection lumen. The supplied fluid flows through the injection lumen and its distal end into the return lumen to cool the surrounding areas external to and proximate the distal end of the device.
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公开(公告)号:EP1148833B1
公开(公告)日:2003-07-02
申请号:EP00901435.8
申请日:2000-01-25
IPC分类号: A61B18/02
CPC分类号: A61B18/02 , A61B2017/00092 , A61B2017/00119 , A61B2018/0212 , A61B2018/0262 , A61F7/12
摘要: A surgical device includes a device body defining a sealed fluid path having a first end and a second end, a refrigerant supply in communication with the first end of the sealed fluid path, and a vacuum source in communication with the second end of the sealed fluid path. Leak detection apparatus can be provided in communication with the sealed fluid path.
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