公开(公告)号：EP2150350A1

公开(公告)日：2010-02-10

申请号：EP08767853.8

申请日：2008-05-23

申请人： The Regents of the University of California ,  Cynvenio Biosystems, Llc

发明人： SOH, Hyongsok ,  FERGUSON, Brian Scott ,  ZHANG, Yanting ,  STAGLIANO, Nancy, E.

IPC分类号： B03C1/00

CPC分类号： B03C1/015 ,  B01L3/502761 ,  B01L2200/0636 ,  B01L2200/0668 ,  B03C1/286 ,  B03C1/288 ,  B03C5/028 ,  B03C2201/18 ,  B03C2201/26

摘要： A fluidic device employs one or more sorting stations for separating target species from other species in a sample. At least one of the sorting stations employs a magnetic field gradient to accomplish separation. In addition, the sorting station is integrated on a single substrate with one or more other modules for processing the sample. For example, the fluidic device may include both a sorting station and a separate trapping station that holds some or all components of the sample for additional processing. The trapping station may be located at a position upstream or downstream from the sorting module.

摘要翻译： 流体装置采用一个或多个分选站来从样品中的其他物种中分离目标物质。 至少有一个分选站采用磁场梯度来完成分离。 另外，分拣站与一个或多个用于处理样本的其他模块集成在单个基底上。 例如，流体装置可以包括分拣站和单独的捕获站，该捕获站容纳样本的一些或全部组件以用于附加处理。 诱捕站可以位于分拣模块的上游或下游的位置。

公开(公告)号：EP2150350B1

公开(公告)日：2012-04-25

申请号：EP08767853.8

申请日：2008-05-23

申请人： The Regents of the University of California ,  Cynvenio Biosystems, Llc

发明人： SOH, Hyongsok ,  FERGUSON, Brian Scott ,  ZHANG, Yanting ,  STAGLIANO, Nancy, E.

IPC分类号： B03C1/015 ,  B03C1/28 ,  B03C5/02

CPC分类号： B03C1/015 ,  B01L3/502761 ,  B01L2200/0636 ,  B01L2200/0668 ,  B03C1/286 ,  B03C1/288 ,  B03C5/028 ,  B03C2201/18 ,  B03C2201/26

摘要： A fluidic device employs one or more sorting stations for separating target species from other species in a sample. At least one of the sorting stations employs a magnetic field gradient to accomplish separation. In addition, the sorting station is integrated on a single substrate with one or more other modules for processing the sample. For example, the fluidic device may include both a sorting station and a separate trapping station that holds some or all components of the sample for additional processing. The trapping station may be located at a position upstream or downstream from the sorting module.

公开(公告)号：EP2178646A1

公开(公告)日：2010-04-28

申请号：EP08798560.2

申请日：2008-08-22

申请人： Cynvenio Biosystems, LLC

发明人： CHANG-YEN, David, A. ,  DARABI, Jafar ,  ZHANG, Yanting ,  SOH, Hyongsok, T. ,  PAGANO, Paul

IPC分类号： B03C1/28 ,  B03C1/01

CPC分类号： B03C1/288 ,  B03C1/01 ,  B03C2201/26

摘要： A system for sorting and trapping magnetic target species includes a microfluidic trapping module designed to receive and then temporarily hold magnetic particles in place within the module. The magnetic particles flowing into the module are trapped there while the other sample components (non-magnetic) continuously flow through and out of the station, thereby separating and concentrating the species captured on the magnetic particles. The magnetic particles and/or their payloads may be released and separately collected at an outlet after the sample passes through the trapping module.