公开(公告)号：EP1758904B1

公开(公告)日：2009-06-03

申请号：EP04745116.6

申请日：2004-06-11

申请人： DABUR PHARMA LTD.

发明人： Seshagiri, V. Indian Institute of Chemical Biology ,  Mukherjee, Rama Dabur Research Foundation ,  Burman, Anand C. Dabur Research Foundation ,  Gurjar, Mukund K. National Chemical Laboratory ,  Yadav, J. S. Indian Inst. of Chemical Technology ,  Jaggi, Manu Dabur Research Foundation ,  Singh, Anu T. Dabur Research Foundation ,  Srivastava, Sanjay K. Dabur Research Foundation ,  Jaisankar, P. Indian Institute of Chemical Biology ,  Pal, Bikash Indian Institute of Chemical Biology ,  Banerjee,Asish K. Indian Inst. of Chemical Biology ,  Wakharkar, Radhika D. National Chemical Laboratory

IPC分类号： C07D471/14 ,  A61K31/407 ,  A61P35/00

CPC分类号： C07D471/14

摘要： The present invention relates to novel derivatives of flavopereirine and methods for manufacture thereof. The novel derivatives of flavopereirine are useful for inhibition or prevention of the growth or multiplication of cancer cells, and to therapeutic compositions containing such compounds. The invention more specifically relates to the use of derivatives of flavopereirine for the inhibition and / or prevention of cancer of the ovary, breast, prostate, pancreas, oral cavity, lung, colon, and larynx.

公开(公告)号：EP1758904A1

公开(公告)日：2007-03-07

申请号：EP04745116.6

申请日：2004-06-11

申请人： DABUR PHARMA LTD.

发明人： Seshagiri, V. Indian Institute of Chemical Biology ,  Mukherjee, Rama Dabur Research Foundation ,  Burman, Anand C. Dabur Research Foundation ,  Gurjar, Mukund K. National Chemical Laboratory ,  Yadav, J. S. Indian Inst. of Chemical Technology ,  Jaggi, Manu Dabur Research Foundation ,  Singh, Anu T. Dabur Research Foundation ,  Srivastava, Sanjay K. Dabur Research Foundation ,  Jaisankar, P. Indian Institute of Chemical Biology ,  Pal, Bikash Indian Institute of Chemical Biology ,  Banerjee,Asish K. Indian Inst. of Chemical Biology ,  Wakharkar, Radhika D. National Chemical Laboratory

IPC分类号： C07D471/14 ,  A61K31/407 ,  A61P35/00

CPC分类号： C07D471/14

摘要： The present invention relates to novel derivatives of flavopereirine and methods for manufacture thereof. The novel derivatives of flavopereirine are useful for inhibition or prevention of the growth or multiplication of cancer cells, and to therapeutic compositions containing such compounds. The invention more specifically relates to the use of derivatives of flavopereirine for the inhibition and / or prevention of cancer of the ovary, breast, prostate, pancreas, oral cavity, lung, colon, and larynx.