公开(公告)号：EP0339252A2

公开(公告)日：1989-11-02

申请号：EP89104962.9

申请日：1989-03-20

申请人： DAINIPPON INK AND CHEMICALS, INC. ,  KAWAMURA INSTITUTE OF CHEMICAL RESEARCH

发明人： Masashi, Osawa ,  Tadao, Shoji ,  Sadao, Takehara ,  Hiroshi, Ogawa ,  Toru, Fujisawa ,  Takeshi, Kuriyama ,  Kayoko, Nakamura

IPC分类号： C07D241/12 ,  C09K19/34 ,  C07D239/26

CPC分类号： C07D239/26 ,  C07D241/12 ,  C09K19/3452

摘要： A 2,5-disubstituted pyrazine derivaitve and a 2,5-­disubstituted pyrimidine derivative of the formula (I):
wherein R¹ and R² each independently represents a straight chain or branched alkyl group containing 1 to 20 carbon atoms;
X represents a halogen atom; and
represents a pyrazine-2,5-diyl or a pyrimidine-2,5-diyl group;
each useful as an electrooptical display material are disclosed. Further a liquid crystal composition comprising said compounds as well as a ferroelectric display device wherein said liquid crystal composition is used are disclosed.

摘要翻译： 2,5-二取代吡嗪衍生物和式（I）的2,5-二取代嘧啶衍生物：其中R 1和R 2各自独立地表示直链或支链烷基，其含有1〜 20个碳原子; X表示卤原子; 和表示吡嗪-2,5-二基或嘧啶-2,5-二基; 各自用作电光显示材料。 此外，还公开了包含所述化合物的液晶组合物以及其中使用所述液晶组合物的铁电显示装置。

公开(公告)号：EP0339252A3

公开(公告)日：1990-11-22

申请号：EP89104962.9

申请日：1989-03-20

申请人： DAINIPPON INK AND CHEMICALS, INC. ,  KAWAMURA INSTITUTE OF CHEMICAL RESEARCH

发明人： Masashi, Osawa ,  Tadao, Shoji ,  Sadao, Takehara ,  Hiroshi, Ogawa ,  Toru, Fujisawa ,  Takeshi, Kuriyama ,  Kayoko, Nakamura

IPC分类号： C07D241/12 ,  C09K19/34 ,  C07D239/26

CPC分类号： C07D239/26 ,  C07D241/12 ,  C09K19/3452

摘要： A 2,5-disubstituted pyrazine derivaitve and a 2,5-­disubstituted pyrimidine derivative of the formula (I):
wherein R¹ and R² each independently represents a straight chain or branched alkyl group containing 1 to 20 carbon atoms;
X represents a halogen atom; and
represents a pyrazine-2,5-diyl or a pyrimidine-2,5-diyl group;
each useful as an electrooptical display material are disclosed. Further a liquid crystal composition comprising said compounds as well as a ferroelectric display device wherein said liquid crystal composition is used are disclosed.

公开(公告)号：EP0339252B1

公开(公告)日：1996-06-12

申请号：EP89104962.9

申请日：1989-03-20

申请人： DAINIPPON INK AND CHEMICALS, INC. ,  KAWAMURA INSTITUTE OF CHEMICAL RESEARCH

发明人： Masashi, Osawa ,  Tadao, Shoji ,  Sadao, Takehara ,  Hiroshi, Ogawa ,  Toru, Fujisawa ,  Takeshi, Kuriyama ,  Kayoko, Nakamura

IPC分类号： C07D241/12 ,  C09K19/34 ,  C07D239/26

CPC分类号： C07D239/26 ,  C07D241/12 ,  C09K19/3452

公开(公告)号：EP0532026A3

公开(公告)日：1993-10-06

申请号：EP92115574.3

申请日：1992-09-11

申请人： DAINIPPON INK AND CHEMICALS, INC.

发明人： Tadao, Shoji ,  Takahashi, Nahoko ,  Ikushima, Naoya ,  Uryu, Toshiyuki ,  Yoshida, Takashi ,  Yamamoto, Naoki ,  Nakashima, Hideki ,  Katsuraya, Kaname ,  Adachi, Koichiro ,  Kataoka, Fusayo

IPC分类号： C07H15/203 ,  A61K31/70 ,  C08B37/00 ,  A61K31/72

CPC分类号： C07H15/203 ,  C08B37/006

摘要： A oligosaccharide aromatic glycoside sulfate or a physiologically acceptable salt of the same which is formed from same or different monosaccharides bonded by glycoside bonds, wherein the hydrogen atom in the hydroxyl group at the position-1 carbon atom at the terminal of the oligosaccharide is substituted with a group represented by Formula (I):
        - Y - (O) n - R   (I)
(in the formula, R represents an alkyl group having 1-18 carbon atoms, n is 0 or 1, O represents an oxygen atom, and Y represents an allylene group) and at least 10% of the remaining hydroxyl groups of the sugar subunits have been subjected to sulfated esterification; an anti-viral agent containing this oligosaccharide aromatic glycoside sulfate or physiologically acceptable salt of the same as an active component; and a oligosaccharide aromatic glycoside which functions as a production intermediate are disclosed. The anti-viral agent exhibits low toxicity and superior anti-viral activity, and is especially effective against viruses which are known to cause AIDS.

公开(公告)号：EP0532026A2

公开(公告)日：1993-03-17

申请号：EP92115574.3

申请日：1992-09-11

申请人： DAINIPPON INK AND CHEMICALS, INC.

发明人： Tadao, Shoji ,  Takahashi, Nahoko ,  Ikushima, Naoya ,  Uryu, Toshiyuki ,  Yoshida, Takashi ,  Yamamoto, Naoki ,  Nakashima, Hideki ,  Katsuraya, Kaname ,  Adachi, Koichiro ,  Kataoka, Fusayo

IPC分类号： C07H15/203 ,  A61K31/70 ,  C08B37/00 ,  A61K31/72

CPC分类号： C07H15/203 ,  C08B37/006

摘要： A oligosaccharide aromatic glycoside sulfate or a physiologically acceptable salt of the same which is formed from same or different monosaccharides bonded by glycoside bonds, wherein the hydrogen atom in the hydroxyl group at the position-1 carbon atom at the terminal of the oligosaccharide is substituted with a group represented by Formula (I):



        - Y - (O) n - R   (I)



(in the formula, R represents an alkyl group having 1-18 carbon atoms, n is 0 or 1, O represents an oxygen atom, and Y represents an allylene group) and at least 10% of the remaining hydroxyl groups of the sugar subunits have been subjected to sulfated esterification; an anti-viral agent containing this oligosaccharide aromatic glycoside sulfate or physiologically acceptable salt of the same as an active component; and a oligosaccharide aromatic glycoside which functions as a production intermediate are disclosed. The anti-viral agent exhibits low toxicity and superior anti-viral activity, and is especially effective against viruses which are known to cause AIDS.

摘要翻译： 由通过糖苷键键合的相同或不同的单糖形成的寡糖芳香糖苷硫酸盐或其生理学上可接受的盐，其中寡糖末端的位置-1个碳原子上的羟基中的氢原子被 式（I）表示的基团：-Y - （O）n -R（I>（式中，R表示碳原子数1〜18的烷基，n表示0或1，O表示氧原子， Y表示烯丙基），并且将糖亚基的剩余羟基中的至少10％进行硫酸酯化反应，含有该寡糖芳香族糖苷硫酸盐的抗病毒剂或与活性成分相同的生理学上可接受的盐 ;和作为生产中间体发挥作用的寡糖芳香糖苷，抗病毒剂具有低毒性和优良的抗病毒活性，特别有效对抗 已知导致艾滋病的病毒。