公开(公告)号：EP1578929A4

公开(公告)日：2006-12-13

申请号：EP03761273

申请日：2003-06-23

申请人： DIVERGENCE INC

发明人： WILLIAMS DERYCK J ,  MCLAIRD MERRY B ,  HRESKO MICHELLE COUTU ,  FREVERT ANITA M ,  WORTHINGTON RONALD E ,  KLOEK ANDREW P ,  DAVILA-APONTE JENNIFER A ,  BRADLEY JOHN D ,  XU SIQUN

IPC分类号： C12N9/10 ,  C12N9/00 ,  C07H21/04 ,  C07K16/00 ,  G01N33/53

CPC分类号： C12N9/1007

摘要： Nucleic acid molecules from nematodes encoding phosphoethanolamine n-methyltransferase polypeptides are described. PEAMT-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PEAMT-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production

摘要翻译： 描述了编码磷酸乙醇胺正甲基转移酶多肽的线虫的核酸分子。 还提供了PEAMT样多肽序列，载体，宿主细胞以及用于产生PEAMT样核苷酸和多肽的重组方法也是如此。 还描述了用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。