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公开(公告)号:EP2274323A1
公开(公告)日:2011-01-19
申请号:EP09731344.9
申请日:2009-04-07
IPC分类号: C07K14/47 , C07K7/08 , C07K14/025
CPC分类号: C07K7/08 , C07K14/001 , C07K14/47 , C07K2319/00 , C07K2319/21 , C07K2319/23 , C07K2319/41 , C07K2319/42 , C07K2319/43 , G01N33/56983 , G01N2333/025 , G01N2500/00
摘要: The present invention is concerned with means and methods for diagnosing or treating HPV associated neoplasia or tumors. Specifically, it relates to a peptide comprising an amino acid sequence motif as shown in SEQ ID No: 1. Moreover, contemplated by the present invention are fusion polypeptides, polynucleotides, vectors and host cells based on said peptide. Furthermore, the peptides, fusion polypeptides, polynucleotides, and vectors are suitable as pharmaceutical compositions for treating HPV associated neoplasia or tumors. The peptides and fusion polypeptides are also suitable as diagnostic compositions for diagnosing HPV associated neoplasia or tumors. The present invention also refers to a method of identifying a compound capable of binding to the HPV E6 protein. Finally, a kit is provided for carrying out the aforementioned diagnosis or compound identification.
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公开(公告)号:EP2274323B1
公开(公告)日:2014-12-31
申请号:EP09731344.9
申请日:2009-04-07
IPC分类号: C07K7/08 , C07K14/47 , G01N33/569
CPC分类号: C07K7/08 , C07K14/001 , C07K14/47 , C07K2319/00 , C07K2319/21 , C07K2319/23 , C07K2319/41 , C07K2319/42 , C07K2319/43 , G01N33/56983 , G01N2333/025 , G01N2500/00
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