公开(公告)号：EP4065553A1

公开(公告)日：2022-10-05

申请号：EP21741012.5

申请日：2021-01-15

申请人： Daegu-Gyeongbuk Medical Innovation Foundation ,  PimedBio, Inc.

发明人： IM, Chun Young ,  MIN, Sang Hyun ,  YU, Ji Hoon ,  KO, Eun Bi ,  KIM, So Young ,  LEE, Seungyeon ,  CHOI, Dong Kyu ,  LEE, Heejin ,  PARK, Ga Young ,  LEE, Doohyun ,  HONG, Eunmi ,  JEON, Hui-Jeon ,  PARK, Young-Hoon ,  HAN, Ye Ri ,  KIM, Nam Hui ,  KIM, Jun Woo ,  OH, Bae Jun ,  PARK, Jeong-Eun ,  SEO, Chang Hoon ,  SONG, Minsoo ,  RO, Seonggu ,  SHIN, Dongkyu

IPC分类号： C07C311/16 ,  C07C303/36 ,  A61K31/18 ,  A61P35/00 ,  A61P29/00 ,  A61P3/00 ,  A23L33/10

公开(公告)号：EP4230624A1

公开(公告)日：2023-08-23

申请号：EP21869736.5

申请日：2021-09-16

申请人： The Asan Foundation ,  Daegu-Gyeongbuk Medical Innovation Foundation ,  University Of Ulsan Foundation For Industry Cooperation

发明人： HWANG, Jung Jin ,  PARK, Sang Eun ,  KIM, Dong Eun ,  HONG, Ji-Ye ,  KIM, Choung-Soo ,  SON, Woo Chan ,  KIM, Shinae ,  KWON, Sugyeong ,  JUNG, Kyungjin ,  KIM, Nayeon ,  KIM, Jina ,  KIM, Kyung-Hee ,  CHIN, Jung Wook ,  CHO, Sung Jin ,  LEE, Sehan ,  CHA, Eunju ,  JOO, Jeongmin ,  HWANG, Ji Sun ,  PARK, Jeong-Eun ,  YU, Ji Hoon ,  HONG, Eunmi ,  PARK, Young-Hoon ,  LEE, Ju-Hee

IPC分类号： C07D401/14 ,  A61K31/517 ,  A61K31/5377 ,  A61K31/55 ,  A61P35/00 ,  C07D401/12 ,  A23L33/10

摘要： A compound, a stereoisomer thereof, a hydrate thereof, or a pharmaceutically acceptable salt thereof, provided as one aspect of the present invention, exhibits a high inhibitory ability on euchromatic histone-lysine N-methyltransferase 2 (EHMT2), and thus, the compound can be usefully used for the treatment of cancer.