专利检索 ap:("Daiichi Asubio Pharma Co., Ltd.") AND inv:"YOSHIKAWA, Junichi" 第 1 页

1.

发明授权
PREVENTIVES OR REMEDIES FOR DISEASES INDUCED BY HYPOFUNCTION OF NITRIC OXIDE SYNTHASE (NOS) 失效
标题翻译：造成的氮氧化氮合酶LACK（NOS）用于疾病的预防或治疗剂跳闸ARE

公开(公告)号：EP0908182B2

公开(公告)日：2007-03-28

申请号：EP97937845.2

申请日：1997-08-29

申请人： Daiichi Asubio Pharma Co., Ltd.

发明人： ISHIHARA, Takafumi , KANAYAMA, Yoshiharu , OKAMURA, Mikio , YOSHIKAWA, Junichi , SHINTAKU, Haruo

IPC分类号： A61K31/505 , A61P37/00 , A61P25/00 , A61P9/00 , A61P1/00

CPC分类号： A61K31/525 , A61K31/519 , C07D475/04

摘要： Remedies containing as the active ingredient compounds represented by general formula (I) or pharmaceutically acceptable salts thereof, whereby diseases induced by the hypofunction of NOS can be efficaciously prevented or ameliorated, wherein R?1 and R2¿ represent each hydrogen, or R?1 and R2¿ form together a single bond; and R3 represents -CH(OH)CH(OH)CH¿3?, CH(OCOCH3)CH(OCOCH3)CH3, -CH3, -CH2OH or phenyl when R?1 and R2¿ are hydrogen, or R3 represents -COCH(OH)CH¿3? when R?1 and R2¿ form together a single bond.