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公开(公告)号：EP4374852A3
公开(公告)日：2024-09-25
申请号：EP24164945.8
申请日：2018-05-14
IPC分类号： C12N15/13 , A61K9/00 , A61K31/4745 , A61K39/395 , A61K47/68 , A61P13/12 , A61P15/08 , A61P35/00 , A61P43/00 , C07K16/28 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12P21/08 , A61K9/08 , A61K9/19 , A61K39/00 , C12N5/16
CPC分类号： A61K31/4745 , A61P13/12 , A61P15/08 , A61P35/00 , C07K16/28 , A61K9/0019 , A61K9/08 , A61K47/26 , A61K47/10 , A61K9/0021 , A61K9/19 , C07K2317/7720130101 , C07K2317/3320130101 , C07K2317/2420130101 , C07K2317/9220130101 , C07K2317/7320130101 , A61K2039/50520130101 , C12N2510/0220130101 , C12N5/163 , C12N5/16 , A61K47/6849 , A61K47/6851 , A61K47/6861 , A61K47/6869 , A61K47/68033 , A61K47/68037
摘要： It is an object of the present invention to provide an antibody binding to CDH6 and having internalization activity, an antibody-drug conjugate of the antibody and a drug having antitumor activity, a pharmaceutical product comprising the antibody-drug conjugate and having therapeutic effects on a tumor, a method for treating a tumor using the antibody, the antibody-drug conjugate or the pharmaceutical product, and the like. The present invention provides an anti-CDH6 antibody having internalization activity, an antibody-drug conjugate of the antibody and a drug having antitumor activity, a pharmaceutical product comprising the antibody or the antibody-drug conjugate, and a method for treating a tumor.
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公开(公告)号：EP4374852A2
公开(公告)日：2024-05-29
申请号：EP24164945.8
申请日：2018-05-14
IPC分类号： A61K9/19
CPC分类号： A61K31/4745 , A61P13/12 , A61P15/08 , A61P35/00 , C07K16/28 , A61K9/0019 , A61K9/08 , A61K47/26 , A61K47/10 , A61K9/0021 , A61K9/19 , C07K2317/7720130101 , C07K2317/3320130101 , C07K2317/2420130101 , C07K2317/9220130101 , C07K2317/7320130101 , A61K2039/50520130101 , C12N2510/0220130101 , C12N5/163 , C12N5/16 , A61K47/6849 , A61K47/6851 , A61K47/6861 , A61K47/6869 , A61K47/68033 , A61K47/68037
摘要： It is an object of the present invention to provide an antibody binding to CDH6 and having internalization activity, an antibody-drug conjugate of the antibody and a drug having antitumor activity, a pharmaceutical product comprising the antibody-drug conjugate and having therapeutic effects on a tumor, a method for treating a tumor using the antibody, the antibody-drug conjugate or the pharmaceutical product, and the like. The present invention provides an anti-CDH6 antibody having internalization activity, an antibody-drug conjugate of the antibody and a drug having antitumor activity, a pharmaceutical product comprising the antibody or the antibody-drug conjugate, and a method for treating a tumor.
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