公开(公告)号：EP1973837B1

公开(公告)日：2017-04-19

申请号：EP06851496.7

申请日：2006-12-22

申请人： Dermazone Solutions, Inc.

发明人： FOUNTAIN, Michael, W.

IPC分类号： A61K9/127 ,  A61K9/51

CPC分类号： A61K9/5123 ,  A61K8/14 ,  A61K8/42 ,  A61K8/4953 ,  A61K8/553 ,  A61K8/602 ,  A61K8/67 ,  A61K8/673 ,  A61K9/0014 ,  A61K9/0053 ,  A61K9/1075 ,  A61K9/127 ,  A61K9/1271 ,  A61K9/14 ,  A61K9/51 ,  A61K9/5107 ,  A61K31/122 ,  A61K31/167 ,  A61K31/375 ,  A61K31/522 ,  A61K31/7048 ,  A61K31/714 ,  A61K2800/10 ,  A61K2800/413 ,  A61K2800/92 ,  A61Q19/00 ,  Y10S977/773 ,  Y10S977/797 ,  Y10S977/906 ,  Y10S977/907

摘要： Nanolipidic Particles (NLPs) having average mean diameters of 1 nm to 20 nm are made from a precursor solution. NLPs can be loaded with a desired passenger molecule. Assemblies of these particles, called NLP assemblies, result in a vehicle population of a desired size. Single application or multifunction NLP assemblies are made from the loaded NLPs and range in size from about 30 to about 200 nm. A method of using preloaded NLPs to make larger carrier vehicles or a mixed population provides increased encapsulation efficiency. NLPs have application in the cosmetics, pharmaceutical, and food and beverage industries.

摘要翻译： 平均直径为1nm〜20nm的纳米脂质颗粒（NLP）由前体溶液制成。 NLP可以装载所需的乘客分子。 称为NLP组件的这些粒子的组件导致所需尺寸的车辆总数。 单一应用或多功能NLP组件由加载的NLP制成，尺寸范围为约30至约200nm。 使用预加载的NLP来制造更大载体载体或混合群体的方法提供了提高的封装效率。 NLP适用于化妆品，制药和食品饮料行业。

公开(公告)号：EP1973837A2

公开(公告)日：2008-10-01

申请号：EP06851496.7

申请日：2006-12-22

申请人： Dermazone Solutions, Inc.

发明人： FOUNTAIN, Michael, W.

IPC分类号： B82B3/00

CPC分类号： A61K9/5123 ,  A61K8/14 ,  A61K8/42 ,  A61K8/4953 ,  A61K8/553 ,  A61K8/602 ,  A61K8/67 ,  A61K8/673 ,  A61K9/0014 ,  A61K9/0053 ,  A61K9/1075 ,  A61K9/127 ,  A61K9/1271 ,  A61K9/14 ,  A61K9/51 ,  A61K9/5107 ,  A61K31/122 ,  A61K31/167 ,  A61K31/375 ,  A61K31/522 ,  A61K31/7048 ,  A61K31/714 ,  A61K2800/10 ,  A61K2800/413 ,  A61K2800/92 ,  A61Q19/00 ,  Y10S977/773 ,  Y10S977/797 ,  Y10S977/906 ,  Y10S977/907

摘要： Nanolipidic Particles (NLPs) having average mean diameters of 1 nm to 20 nm are made from a precursor solution. NLPs can be loaded with a desired passenger molecule. Assemblies of these particles, called NLP assemblies, result in a vehicle population of a desired size. Single application or multifunction NLP assemblies are made from the loaded NLPs and range in size from about 30 to about 200 nm. A method of using preloaded NLPs to make larger carrier vehicles or a mixed population provides increased encapsulation efficiency. NLPs have application in the cosmetics, pharmaceutical, and food and beverage industries.