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公开(公告)号:EP1826264A1
公开(公告)日:2007-08-29
申请号:EP06003847.8
申请日:2006-02-24
发明人: Kaup, Franz-Josef, Prof. Dr. , Mätz-Rensing, Kerstin, Dr. , Stahl-Hennig, Christiane, Dr. , Pauli, Georg, Prof. , Ellerbrok, Heinz, Dr.
IPC分类号: C12N7/00 , C07K14/065 , A61K35/76 , A61K39/275
CPC分类号: C12N7/00 , A01K2227/106 , A01K2267/0337 , A61K39/12 , A61K39/275 , A61K49/0008 , C12N2710/24132 , G01N33/56983 , G01N2333/065
摘要: The present invention is directed to an animal model for predicting the course of orthopox virus infections or for evaluating the efficacy of anti-viral therapeutics or anti-orthopox virus vaccines. The present invention is further directed to a method of evaluating the efficacy of an anti-viral therapeutic or an anti-orthopox virus vaccine and to a specific Callithrixpox virus strain for use in this method. Furthermore, the present invention pertains to a pharmaceutical composition containing such an anti-viral therapeutic or an anti-orthopox virus vaccine.
摘要翻译: 本发明涉及用于预测正痘病毒感染过程或用于评估抗病毒治疗剂或抗痘痘病毒疫苗的功效的动物模型。 本发明进一步涉及一种评价抗病毒治疗剂或抗原疱疹病毒疫苗和用于该方法的特定Callithrixpox病毒株的功效的方法。 此外,本发明涉及含有这种抗病毒治疗剂或抗原疱疹病毒疫苗的药物组合物。