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1.发明授权SUBSTITUTED HETEROCYCLIC COMPOUNDS AS TROPOMYOSIN RECEPTOR KINASE A (TRKA) INHIBITORS 有权作为肌动蛋白受体激酶A（TRKA）抑制剂的取代的杂环化合物
公开(公告)号：EP2791139B1
公开(公告)日：2017-11-08
申请号：EP12834589.9
申请日：2012-12-12
发明人： SASMAL, Pradip, Kumar , AHMED, Shahadat , PRABHU, Ganesh , TEHIM, Ashok , PARADKAR, Vidyadhar , DATTATREYA, Marahanakuli, Prasanna , MAVINAHALLI, Nanjegowda, Jagadeesh
IPC分类号： C07D471/04 , A61K31/437 , A61P29/00 , A61P35/00 , C07D519/00
CPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/4995 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K31/635 , C07D519/00 , Y02A50/414
摘要： The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.
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2.发明公开SUBSTITUTED HETEROCYCLIC COMPOUNDS AS TROPOMYOSIN RECEPTOR KINASE A (TRKA) INHIBITORS 有权替加利异丁烯酸酯VERBINDUNGEN ALS TROPOMYOSIN-REZEPTOR-KINASE-A（TRKA）-INHIBITOREN
公开(公告)号：EP2791139A1
公开(公告)日：2014-10-22
申请号：EP12834589.9
申请日：2012-12-12
发明人： SASMAL, Pradip, Kumar , AHMED, Shahadat , PRABHU, Ganesh , TEHIM, Ashok , PARADKAR, Vidyadhar , DATTATREYA, Marahanakuli, Prasanna , MAVINAHALLI, Nanjegowda, Jagadeesh
IPC分类号： C07D471/04 , A61K31/437 , A61P29/00 , A61P35/00 , C07D519/00
CPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/4995 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K31/635 , C07D519/00 , Y02A50/414
摘要： The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.
摘要翻译： 本申请涉及一系列取代的吡唑并[1,5-a]吡啶化合物，它们用作原肌球蛋白受体激酶（Trk）家族蛋白激酶抑制剂，制备方法和包含这些化合物的药物组合物。
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3.发明公开SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF PAIN 审中-公开替加利米咪唑[1,2-A]吡啶 - 维生素ZUR BEHANDLUNG VON SCHMERZEN
公开(公告)号：EP3157921A1
公开(公告)日：2017-04-26
申请号：EP15735808.6
申请日：2015-06-23
申请人： Dr. Reddy's Laboratories Ltd. , Sasmal, Pradip Kumar , Ahmed, Shahadat , Tehim, Ashok , Paradkar, Vidyadhar
IPC分类号： C07D471/04 , A61K31/437 , A61P35/04
CPC分类号： A61K31/437 , A61K31/4025 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/501 , A61K31/5377 , A61K31/55 , A61K31/635 , C07D471/04 , C07K5/06 , Y02A50/414
摘要： The present application relates to a series of substituted imidazo[1,2-a]pyridine compounds of formula (I), pharmaceutically acceptable salts, pharmaceutically acceptable solvates or stereoisomers thereof, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.
摘要翻译： 本申请涉及式（I）的一系列取代的咪唑并[1,2-a]吡啶化合物，其药学上可接受的盐，药学上可接受的溶剂合物或立体异构体，其用作原肌球蛋白受体激酶（Trk）家族蛋白激酶抑制剂， 制备方法和包含这些化合物的药物组合物。
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