专利检索 ap:("Dr. Reddy's Laboratories Ltd." OR "Dr. Reddy's Laboratories Inc.") AND inv:"MEESALA, V. Madhu Babu" 第 1 页

1.

发明公开
PROCESS FOR THE PREPARATION OF A SINGLE ENANTIOMER OF 3-AMINOPIPERIDINE DIHYDROCHLORIDE 审中-公开
标题翻译：方法用于生产单一对映体OFF 3-氨基二盐酸盐

公开(公告)号：EP2582671A2

公开(公告)日：2013-04-24

申请号：EP11796521.0

申请日：2011-06-17

申请人： Dr. Reddy's Laboratories Ltd. , Dr. Reddy's Laboratories Inc.

发明人： MEEK, Graham Andrew , KUNHIMON, Syam Kumar Unniaran Purakkal , SHANKAR, R. , DAHANUKAR, Vilas Hareshwar , MOHAN, TH. Krishna , WAGH, Manoj Balu , PAL, Abir Kumar , MEESALA, V. Madhu Babu , SHRIVASTAVA, Sonmit

IPC分类号： C07D211/56 , B01J23/44 , C07B55/00

CPC分类号： C07D211/02 , B01J21/18 , B01J23/44 , C07B57/00 , C07D211/56

摘要： A process comprising: (a) reduction of N-acetyl-3-aminopyridine (2): or its salt in the presence of hydrogen and a palladium catalyst deposited on solid support; (b) converting racemic N-acetyl-3-aminopiperidine (3) or its salt produced in step (a) to rac-3-aminopiperidine (rac-4) or its salt; (c) resolution of the racemic 3-aminopiperidine (rac-4) or its salt produced in step (b) with a chiral acid.