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公开(公告)号：EP2986628A1
公开(公告)日：2016-02-24
申请号：EP14785257.8
申请日：2014-04-15
申请人： Duke University , The Government of The US, as Represented by The Secretary of the Army, on behalf of Walter Reed Army Institute of Research , The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. , Los Alamos National Security, LLC
CPC分类号： C07K14/005 , A61K39/12 , A61K2039/70 , C12N7/00 , C12N2740/16122 , C12N2740/16134
摘要： The present invention relates, in general, to human immunodeficiency virus-1 (HIV - 1) particular, to a polyvalent vaccine for HIV -1 and to methods of making and using same.
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公开(公告)号：EP2739300B1
公开(公告)日：2019-06-19
申请号：EP12807743.5
申请日：2012-07-05
申请人： Duke University , Children's Medical Center Corporation , The Government of The US, as Represented by The Secretary of the Army, on behalf of Walter Reed Army Institute of Research
IPC分类号： A61K38/17 , A61K38/16 , A61K39/245 , A61K48/00 , A61P37/00 , A61P31/00 , A61K39/21 , C07K14/005
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公开(公告)号：EP2739300A2
公开(公告)日：2014-06-11
申请号：EP12807743.5
申请日：2012-07-05
申请人： Duke University , Children's Medical Center Corporation , The Government of The US, as Represented by The Secretary of the Army, on behalf of Walter Reed Army Institute of Research
CPC分类号： C07K14/005 , A61K38/00 , A61K39/12 , A61K39/21 , A61K2039/6075 , C07K16/1063 , C07K2317/21 , C07K2317/55 , C07K2317/92 , C07K2319/40 , C12N2710/16622 , C12N2740/16122 , C12N2740/16134
摘要： The present invention relates, in general, to human immunodeficiency virus (HIV), and in particular to a vaccine for HIV-1 and to methods of making and using same.
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公开(公告)号：EP2900693A1
公开(公告)日：2015-08-05
申请号：EP13841395.0
申请日：2013-09-26
申请人： Duke University , The Government of The US, as Represented by The Secretary of the Army, on behalf of Walter Reed Army Institute of Research
发明人： HAYNES, Barton F. , BONSIGNORI, Mattia , LIAO, Hua-xin , FERRARI, Guido , MOODY, Michael A. , KIM, Jerome , MICHAEL, Nelson , POLLARA, Justin
CPC分类号： C07K16/1063 , A61K39/42 , A61K2039/507 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/732 , C07K2317/76
摘要： The present invention relates, in general, to antibody-dependent cellular cytoxicity (ADCC)-mediating antibodies, and, in particular, to ADCC-mediating antibodies (and fragments thereof) suitable for use, for example, in reducing the risk of HIV-1 infection in a subject. The invention further relates to compositions comprising such antibodies or antibody fragents.
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公开(公告)号：EP2788026A2
公开(公告)日：2014-10-15
申请号：EP12854613.2
申请日：2012-12-05
申请人： Duke University , The Government of The United States, as represented by The Secretary of The Army, on behalf of Walter Reed Army , New York University
CPC分类号： C07K14/005 , A61K39/12 , A61K39/21 , C07K14/162 , C07K16/1063 , C07K2317/34 , C07K2317/55 , C07K2317/76 , C07K2317/92 , C12N2710/24043 , C12N2740/16034 , C12N2740/16122 , C12N2740/16134
摘要： The present invention relates, in general, to human immunodeficiency virus (HIV), and in particular to a vaccine for HIV-1 and to methods of making and using same.
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公开(公告)号：EP2694542A2
公开(公告)日：2014-02-12
申请号：EP12768353.0
申请日：2012-04-09
申请人： Duke University , The Government of The United States, as represented by The Secretary of The Army, on behalf of Walter Reed Army
发明人： HAYNES, Barton, F. , LIAO, Hua-Xin , MOODY, M., Anthony , TOMARAS, Georgia, D. , KIM, Jerome , MICHAEL, Nelson
CPC分类号： C07K16/087
摘要： The present invention relates, in general to herpes simplex virus (HSV) and, particular, to antibodies that are specific for glycoprotein D (gD) of HSV. The invention also relates to prophylactic and therapeutic uses of such antibodies.
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