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公开(公告)号:EP0874831A1
公开(公告)日:1998-11-04
申请号:EP96944218.0
申请日:1996-12-02
发明人: BROWN, Richard, James , DANIEL, Dilon, J. , FRASIER, Deborah, Ann , HARTZELL, Stephen, Lee , KOETHER, Gerard, Michael , WOJTKOWSKI, Paul, Walter
CPC分类号: C07F9/65181 , C07C281/06 , C07D249/12
摘要: Processes are disclosed for preparing compounds of Formula (I), for preparing a compound of Formula (II), for preparing a compound of Formula (III) and for preparing a compound of Formula (IV), wherein R?3 and R4¿ are each independently H, halogen, cyano, nitro, C¿1?-C6 alkyl, C1-C6 haloalkyl, C2-C6 alkenyl, C2-C6 haloalkenyl, C2-C6 alkynyl, C2-C6 haloalkynyl, C1-C6 alkoxy, C1-C6 haloalkoxy, C2-C6 alkenyloxy, C2-C4 alkoxycarbonyl; or C2-C6 alkynyloxy; R?5¿ is H or C¿1?-C3 alkyl, Lg is halogen, acetoxy, OSO2Q or (a); Q is C1-C6 alkyl, C1-C6 alkenyl, or phenyl optionally substituted with C1-C3 alkyl; R?16 is C¿1-C6 alkyl, C1-C6 alkenyl or phenyl; and Z, R?1 and R2¿ are as defined in the disclosure. Also disclosed are advantageous process sequences and process conditions; as well as novel compounds of Formula (III) and novel compounds of Formula (IV).