专利检索 ap:("E.I. DU PONT DE NEMOURS AND COMPANY" OR "MERCK & CO. INC.") AND inv:"ROSSANO, LUCIUS, THOMAS" 第 1 页

1.

发明公开
TETRAZOLYLPHENYLBORONIC ACID INTERMEDIATES FOR THE SYNTHESIS OF AII RECEPTOR ANTAGONISTS. 失效
标题翻译：用于合成AII受体拮抗剂的四氢唑基硼酸中间体。

公开(公告)号：EP0643704A4

公开(公告)日：1995-04-12

申请号：EP93900550

申请日：1992-11-18

申请人： E.I. DU PONT DE NEMOURS AND COMPANY , MERCK & CO. INC.

发明人： LO, YOUNG, SEK , ROSSANO, LUCIUS, THOMAS , LARSEN, ROBERT, D. , KING, ANTHONY, O.

IPC分类号： C07D257/04 , C07B61/00 , C07D257/00 , C07D403/10 , C07F5/02 , C07F5/05

CPC分类号： C07F5/05 , C07F5/025

摘要： Novel tetrazolylphenylboronic acids, methods for their preparation and methods for preparing biphenyltetrazole compounds which are angiotensin II receptor antagonists or which are useful intermediates to prepare angiotensin II receptor antagonists. An illustrative biphenyl tetrazole compound is 2-n-butyl-4-chloro-1-[(2'-(tetrazol-5-yl)-1, 1'-biphenyl-4-yl)methyl]-1H-imidazole-5-methanol, potassium salt.