-
1.发明公开2-Thio or oxo-4-aryl or heterocyclo-1,5(2H)-pyrimidinedicarboxylic acid diesters and 3-acyl-5-pyrimidinecarboxylic acids and esters 失效2-硫代羰基-4-芳基杂环基-1,5（2H） - 嘧啶并碳酸酯和3-酰基-5-嘧啶羰基和酯。
公开(公告)号：EP0204317A2
公开(公告)日：1986-12-10
申请号：EP86107536.4
申请日：1986-06-03
IPC分类号： C07D239/22 , C07D401/04 , C07D413/04 , A61K31/505
CPC分类号： C07D239/22 , C07D401/04 , C07D413/04
摘要： Pyrimidine compounds of the formula
wherein X is sulfur or oxygen, Y is R 11 or-O-R 1 , and R 4 is aryl or heterocyclo are disclosed. These compounds are useful as cardiovascular agents, particularly anti-hypertensive agents, due to their calcium entry blocking vasodilator activity.摘要翻译： 公开了式CHEM的嘧啶化合物，其中X是硫或氧，Y是R 11或-O-R 1，R 4是芳基或杂环。 这些化合物由于其钙进入阻断血管扩张剂活性而可用作心血管药物，特别是抗高血压药。
-
2.发明公开2-Thio or oxo-4-aryl or heterocyclo-1,5(2H)-pyrimidinedicarboxylic acid diesters and 3-acyl-5-pyrimidinecarboxylic acids and esters 失效2-硫代或邻 - 4-芳基或杂环基-1,5（2H） - 嘧啶二羧酸和三 - 乙基-5-吡啶甲酰氧基酸和酯
公开(公告)号：EP0204317A3
公开(公告)日：1987-12-16
申请号：EP86107536
申请日：1986-06-03
IPC分类号： C07D239/22 , C07D401/04 , C07D413/04 , A61K31/505
CPC分类号： C07D239/22 , C07D401/04 , C07D413/04
摘要： Pyrimidine compounds of the formula
wherein X is sulfur or oxygen, Y is R 11 or-O-R 1 , and R 4 is aryl or heterocyclo are disclosed. These compounds are useful as cardiovascular agents, particularly anti-hypertensive agents, due to their calcium entry blocking vasodilator activity.
-
搜索结果
2 条记录 (耗时 0.011 秒)
