公开(公告)号：EP3730134A1

公开(公告)日：2020-10-28

申请号：EP18893074.7

申请日：2018-12-19

申请人： EA Pharma Co., Ltd.

发明人： KATAOKA Daisuke ,  KUYAMA Kazuo ,  ASANO Kenji ,  WAGATSUMA Hirotaka ,  TSURUTA Atsushi ,  TAKANOHASHI Toshiyuki

IPC分类号： A61K31/198 ,  A61P5/18 ,  C07C275/42

摘要： A medicinal composition for preventing or treating secondary hyperparathyroidism under maintenance dialysis, said medicinal composition comprising 3-[[(2S)-2-amino-2-carboxyethyl]carmaboylamino]-5-chloro-4-methylbenzenesulfonic acid or a pharmaceutically acceptable salt thereof, or a solvate of the same which is to be administered by a predefined route in a predefined dosage. According to the present invention, it is possible to provide a prophylactic or therapeutic agent for secondary hyperparathyroidism under maintenance dialysis, said agent showing reduced side effects or no significant accumulation. This medicinal agent allows easy administration management and has a high safety compared with conventional products.

公开(公告)号：EP3950058A1

公开(公告)日：2022-02-09

申请号：EP20784332.7

申请日：2020-04-02

申请人： EA Pharma Co., Ltd.

发明人： MAKITA Yoshimichi ,  KATAOKA Daisuke ,  KUYAMA Kazuo ,  ASANO Kenji ,  SHIBASAKI Ryotaro ,  YAMAMOTO Akiko ,  WAGATSUMA Hirotaka ,  TSURUTA Atsushi ,  TAKANOHASHI Toshiyuki

IPC分类号： A61P5/18 ,  A61P43/00 ,  A61K9/08 ,  A61K47/02 ,  A61K47/10 ,  A61K47/12 ,  A61K47/26 ,  A61K31/198

摘要： Provided is a medicinal composition having excellent stability, the medicinal composition comprising 3-{[(2S)-2-amino-2-carboxyethyl]carbamoylamino}-5-chloro-4-methylbenzenesulfonic acid, a pharmaceutically acceptable salt thereof, or a solvate thereof, wherein the medicinal composition has a pH of 8.0 or less.