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1.发明公开SALTS OF 2,2-DIMETHYL-1,3-DIOXANE INTERMEDIATES AND PROCESS FOR THE PREPARATION THEREOF 审中-公开2,2-二甲基-1,3- DIOXANINTERMEDIATEN和方法盐类及其
公开(公告)号：EP1178980A1
公开(公告)日：2002-02-13
申请号：EP00927612.2
申请日：2000-05-05
发明人： KOTAY NAGY, Péter , GREFF, Zoltán , BARKOCZY, Jozsef , SIMIG, Gyula , BALAZS, Lászlo , DOMAN, Imre , RATKAI, Zoltán , SERES, Péter , BARTHA, Ferenc , VERECZKEYNE DONATH, Györgyi , NAGY, Kálmán
IPC分类号： C07D319/06
CPC分类号： C07D319/06
摘要： The invention relates to salts of (4R-cis) -(1,1-dimethyl -ethyl) -6-(2-aminoethyl) -2,2-dimethyl -1,3-dioxane -4-acetate of formula (I) formed with organic acids. The new salts according to the invention are stable and can be easily purified by recrystallization. The new salts of the invention are valuable pharmaceutical intermediates which can be used e.g. in the preparation of the hypolipidemic agent having the generic (INN) name atorvastatin. The invention further relates to the preparation of the new salts of the compound of formula (I).
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2.发明公开1,3-DIOXOLO/4,5-H//2,3/BENZODIAZEPINE DERIVATIVES AS AMPA/KAINATE RECEPTOR INHIBITORS 有权1-3二氧杂环戊烯/ 4.5-H // 2,3-苯并二氮杂衍生物作为AMPA /红藻氨酸受体抑制剂
公开(公告)号：EP1015457A1
公开(公告)日：2000-07-05
申请号：EP98939782.3
申请日：1998-08-07
发明人： BARKOCZY, Júzsef , CSELENYAK, Judit , RATKAI, Zoltán , SIMIG, Gyula , BALAZS, Lászlo , DOMAN, Imre , KOTAY NAGY, Péter , GREFF, Zoltán , SERES, Péter , SZABO, Géza , GACSALYI, István , GIGLER, Gábor , GYERTYAN, István , LEVAY, György , KOVACS, Attila , SIMO, Annamária , SZABADOS, Tamás , EGYED, András , VEGH, Miklos , TIHANYI, Károly
IPC分类号： C07D491/04 , A61K31/55
CPC分类号： C07D491/04
摘要： The invention refers to 1,3-dioxolo-/4,5-h//2,3/benzodiazepine derivatives of formula (I), a process for preparing these compounds and to pharmaceutical compositions containing these active substances, which are used to selectively inhibit Ampa/Kainate receptors.
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3.发明授权1,3-DIOXOLO/4,5-H//2,3/BENZODIAZEPINE DERIVATIVES AS AMPA/KAINATE RECEPTOR INHIBITORS 有权1-3二氧杂环戊烯/ 4.5-H // 2,3-苯并二氮杂衍生物作为AMPA /红藻氨酸受体抑制剂
公开(公告)号：EP1015457B1
公开(公告)日：2003-11-26
申请号：EP98939782.3
申请日：1998-08-07
发明人： BARKOCZY, Júzsef , CSELENYAK, Judit , RATKAI, Zoltán , SIMIG, Gyula , BALAZS, Lászlo , DOMAN, Imre , KOTAY NAGY, Péter , GREFF, Zoltán , SERES, Péter , SZABO, Géza , GACSALYI, István , GIGLER, Gábor , GYERTYAN, István , LEVAY, György , KOVACS, Attila , SIMO, Annamária , SZABADOS, Tamás , EGYED, András , VEGH, Miklos , TIHANYI, Károly
IPC分类号： C07D491/04 , A61K31/55
CPC分类号： C07D491/04
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