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1.发明授权PIPERAZINYLALKYLTHIOPYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND A PROCESS FOR THE PREPARATION OF THE NOVEL COMPOUNDS 失效Piperazinylalkylthiopyrimidine衍生物含有药物组合物及其方法
公开(公告)号：EP0901473B1
公开(公告)日：2002-03-13
申请号：EP96935194.9
申请日：1996-10-25
发明人： JAKOCZI, Iván , BOZSING, Dániel , RATZNE SIMONEK, Ildiko , GACSALYI, István , SZENASI, Gábor , SCHMIDT, Eva , MIKLESNE KOVACS, Aniko , BILKEI GORZO, András , BLASKO, Gábor , GYERTYAN, István , NEMETH, Gábor , SIMIG, Gyula , TIHANYI, Károly , EGYED, András
IPC分类号： C07D239/38 , C07D239/22 , C07D239/48 , C07D239/46 , A61K31/505
CPC分类号： C07D239/22 , C07D239/38 , C07D239/47 , C07D239/48
摘要： The invention refers to novel piperazinylalkylthiopyrimidine derivatives of formula (I) being suitable for the treatment of diseases due to pathological alterations of the central nervous system, pharmaceutical compositions containing the above derivatives, and a process for the preparation of the novel compounds.
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2.发明公开NOVEL PIPERAZINYLALKYLTHIOPYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND A PROCESS FOR THE PREPARATION OF THE NOVEL COMPOUNDS 失效Piperazinylalkylthiopyrimidine衍生物含有药物组合物及其方法
公开(公告)号：EP0901473A1
公开(公告)日：1999-03-17
申请号：EP96935194.0
申请日：1996-10-25
发明人： JAKOCZI, Iván , BOZSING, Dániel , RATZNE SIMONEK, Ildiko , GACSALYI, István , SZENASI, Gábor , SCHMIDT, Eva , MIKLESNE KOVACS, Aniko , BILKEI GORZO, András , BLASKO, Gábor , GYERTYAN, István , NEMETH, Gábor , SIMIG, Gyula , TIHANYI, Károly , EGYED, András
CPC分类号： C07D239/22 , C07D239/38 , C07D239/47 , C07D239/48
摘要： The invention refers to novel piperazinylalkylthiopyrimidine derivatives of formula (I) being suitable for the treatment of diseases due to pathological alterations of the central nervous system, pharmaceutical compositions containing the above derivatives, and a process for the preparation of the novel compounds.
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3.发明授权NOVEL PIPERAZINYLALKYLTHIOPYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND A PROCESS FOR THEIR PREPARATION 有权新PIPERAZINYLALKYLTHIOPYRIMIDINE含衍生物的药物组合物及其制备方法
公开(公告)号：EP1194415B1
公开(公告)日：2003-08-20
申请号：EP00944119.7
申请日：2000-06-29
发明人： RATZNE SIMONEK, Ildiko , BOZSING, Dániel , NEMETH, Gábor , SIMIG, Gyula , POSZAVACZ, Lászlo , JAKOCZI, Iván , LEVAY, György , GACSALYI, István , TIHANYI, Károly , WELLMAN, János , EGYED, András
IPC分类号： C07D239/48 , A61K31/505 , A61P25/22
CPC分类号： C07D239/48
摘要： The invention refers to novel piperazinylalkylthiopyrimidine derivatives of formula (I), a process for preparing these compounds and to pharmaceutical compositions containing these active substances. The novel compounds of the formula (I) are useful for the treatment of diseases that form due to diseases of the central nervous system.
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