公开(公告)号：EP1585731A2

公开(公告)日：2005-10-19

申请号：EP03749068.7

申请日：2003-09-12

申请人： ELI LILLY AND COMPANY

发明人： BEAVERS, Lisa, Selsam ,  FINLEY, Don, Richard ,  GADSKI, Robert, Alan ,  HIPSKIND, Philip, Arthur ,  JESUDASON, Cynthia, Darshini ,  PICKARD, Richard, Todd ,  STEVENS, Freddie, Craig ,  SEIDAM ,Christopher ,Stephen

IPC分类号： C07D215/08 ,  C07D215/20 ,  C07D215/06 ,  C07D215/58 ,  C07D215/227 ,  C07D209/26 ,  C07D209/04 ,  C07D209/24 ,  C07D209/22 ,  A61K31/404 ,  A61K31/47 ,  A61P37/00

CPC分类号： C07D215/227 ,  C07D209/04 ,  C07D209/22 ,  C07D209/24 ,  C07D209/26 ,  C07D209/32 ,  C07D215/06 ,  C07D215/08 ,  C07D215/20 ,  C07D215/26 ,  C07D215/58 ,  C07D401/06 ,  C07D403/06 ,  C07D405/06 ,  C07D409/06

摘要： The present invention discloses novel compounds of Formula ( I ) or pharmaceutically acceptable salts thereof which have histamine-H3 receptor antagonist activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I), as well as methods of using them to treat obesity and other histamine H3 receptor-related diseases.