公开(公告)号：EP2734290A4

公开(公告)日：2015-03-25

申请号：EP12814718

申请日：2012-07-23

申请人： EMD MILLIPORE CORP

发明人： KAS ONUR Y ,  KOZLOV MIKHAIL ,  TKACIK GABRIEL ,  NHIEM DAVID ,  GODDARD PHILIP ,  LEON SHERRY ASHBY

IPC分类号： B01D69/12 ,  B01D35/00 ,  B01D39/08 ,  B01D39/16 ,  B01D61/14 ,  B01D69/02 ,  C02F1/44

CPC分类号： B01D69/02 ,  B01D67/0004 ,  B01D2239/025 ,  B01D2239/0618 ,  B01D2239/0631 ,  B01D2239/0654 ,  B01D2323/39 ,  C02F1/444 ,  C02F2303/04

公开(公告)号：EP2694196A4

公开(公告)日：2014-11-19

申请号：EP12765651

申请日：2012-03-30

申请人： EMD MILLIPORE CORP

发明人： KAS ONUR Y ,  KOZLOV MIKHAIL ,  TKACIK GABRIEL ,  NHIEM DAVID ,  LEON SHERRY ASHBY ,  GODDARD PHILIP

IPC分类号： B01D69/12 ,  B01D69/00 ,  B01D69/10 ,  B01D71/06 ,  B01D71/56 ,  D01D5/00

CPC分类号： B01D69/12 ,  B01D71/56 ,  B01D2323/39 ,  B01D2325/02 ,  D01D5/0084

摘要： A composite liquid filtration platform including a composite filtration medium featuring an electrospun polymeric nanofiber layer collected on a porous membrane. When in use, the porous membrane acts as a prefilter used upstream from the polymeric nanofiber layer to remove particles from a liquid stream flowing through the composite filtration structure. The nanofiber layer, positioned downstream from the porous membrane, is used as the retentive layer for critical filtration to provide biosafety assurance, and is responsible for capturing microorganisms like bacteria, mycoplasma or viruses. The composite liquid filtration platform provided herein exhibits permeability advantages over conventional porous membranes or nanofiber mats spun on coarse non-wovens.

公开(公告)号：EP2603611A4

公开(公告)日：2014-08-27

申请号：EP11816795

申请日：2011-07-29

申请人： EMD MILLIPORE CORP

发明人： KAS ONUR Y ,  KOZLOV MIKHAIL ,  TKACIK GABRIEL ,  MOYA WILSON ,  GODDARD PHILIP ,  LEON SHERRY ASHBY ,  HAO JIBIN

IPC分类号： C12Q1/70 ,  B01D67/00 ,  C12M1/12 ,  C12Q1/24 ,  C12R1/92

CPC分类号： B01D39/1623 ,  A61L2/022 ,  B01D39/00 ,  B01D39/04 ,  B01D39/14 ,  B01D39/16 ,  B01D39/1607 ,  B01D39/1615 ,  B01D39/18 ,  B01D61/14 ,  B01D67/0004 ,  B01D67/002 ,  B01D69/02 ,  B01D69/10 ,  B01D2239/0208 ,  B01D2239/0216 ,  B01D2239/025 ,  B01D2239/0442 ,  B01D2239/0631 ,  B01D2239/10 ,  B01D2239/1233 ,  B01D2323/39 ,  B01D2323/42 ,  B01D2325/20 ,  C12N7/00 ,  C12N2740/16051 ,  D01D1/02 ,  D01D5/0092 ,  D01F6/96 ,  D10B2505/04

摘要： A method for removing retroviruses from liquid samples and a nanofiber containing liquid filtration medium that simultaneously exhibits high liquid permeability and high microorganism retention is disclosed. Retroviruses are removed from a liquid by passing the liquid through a porous nanofiber containing filtration medium having a retrovirus LRV greater than about 6, and the nanofiber(s) has a diameter from about 10 nm to about 100 nm. The filtration medium can be in the form of a fibrous electrospun polymeric nanofiber liquid filtration medium mat.