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1.发明授权PROPANOIC ACID DERIVATIVES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS 有权丙烷酸衍生物BY及其受体整合阻碍的结合
公开(公告)号：EP1189881B2
公开(公告)日：2013-01-23
申请号：EP00930450.2
申请日：2000-05-05
发明人： BIEDIGER, Ronald, J. , HOLLAND, George, W. , KASSIR, Jamal, M. , LI, Wen , MARKET, Robert, V. , SCOTT, Ian, L. , WU, Chengde
IPC分类号： C07D405/12 , C07D213/64 , C07D213/89 , C07D409/14
CPC分类号： C07D213/64 , C07D317/60 , C07D405/12 , C07D409/14
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2.发明公开PHENYLENEDIAMINE UROTENSIN-II RECEPTOR ANTAGONISTS AND CCR-9 ANTAGONISTS 审中-公开苯二胺尾加压素II受体拮抗剂和CCR-9拮抗剂
公开(公告)号：EP1610753A2
公开(公告)日：2006-01-04
申请号：EP04712313.8
申请日：2004-02-18
发明人： WU, Chengde , ANDERSON, Eric, C. , BUI, Huong , GAO, Daxin , KASSIR, Jamal , LI, Wen , WANG, Junmei , MARKET, Robert, V.
IPC分类号： A61K6/00
CPC分类号： C07D333/38 , C07D207/16 , C07D209/08 , C07D209/44 , C07D213/74 , C07D237/08 , C07D239/26 , C07D241/42 , C07D295/135 , C07D401/12 , C07D403/12 , C07D409/12
摘要： The present invention relates to urotensin II receptor antagonists, CCR-9 antagonists, pharmaceutical compositions containing them and their use.
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3.发明授权CARBOXYLIC ACID DERIVATIVES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS 有权羧酸衍生物由绑定及其受体整合，以抑制
公开(公告)号：EP1176956B1
公开(公告)日：2008-01-09
申请号：EP00937527.0
申请日：2000-05-05
发明人： BIEDIGER, Ronald, J. , CHEN, Qi , HOLLAND, George, W. , KASSIR, Jamal, M. , LI, Wen , MARKET, Robert, V. , SCOTT, Ian, L. , WU, Chengde
IPC分类号： A61K31/215 , A61K31/335 , A61K31/38 , A61K31/4025 , A61K31/44 , A61K31/4427 , A61K31/445 , A61K31/4523 , A61K31/47 , A61K31/506 , C07C69/66 , C07D207/04 , C07D207/18 , C07D211/68 , C07D211/72 , C07D213/02 , C07D215/00
CPC分类号： C07D213/75 , C07D239/47 , C07D405/12 , C07D409/14
摘要： A method for the inhibition of the binding of α4β1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and to the use of such compounds either as above, or in formulations for the control or prevention of diseases states in which α4β1 is involved.
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4.发明公开PYRIDINE, PYRIMIDINE, QUINOLINE, QUINAZOLINE, AND NAPHTHALENE UROTENSIN-II RECEPTOR ANTAGONISTS. 审中-公开吡啶，嘧啶，喹啉，喹唑啉和萘尾加压素II受体拮抗剂
公开(公告)号：EP1603884A2
公开(公告)日：2005-12-14
申请号：EP04713383.0
申请日：2004-02-20
发明人： WU, Chengde , ANDERSON, C., Eric , BUI, Huong , GAO, Daxin , HOLLAND, George, W. , KASSIR, Jamal , LI, Wen , WANG, Junmei , DUPRE, Brian
IPC分类号： C07D215/44 , A61K31/4706
CPC分类号： C07D215/44 , C07D401/12 , C07D401/14
摘要： The present invention relates to urotensin II receptor antagonists, pharmaceutical compositions containing them and their use.
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