公开(公告)号：EP2125739A1

公开(公告)日：2009-12-02

申请号：EP07863216.3

申请日：2007-12-21

申请人： ENCYSIVE PHARMACEUTICALS, INC.

发明人： BIEDIGER, Ronald J. ,  BUI, Huong ,  HENRY, Kevin M. ,  THRASH, Thomas

IPC分类号： C07D213/81 ,  C07D213/82 ,  C07D279/14 ,  C07D279/22 ,  C07D307/68 ,  C07D333/70 ,  C07D401/06 ,  C07D401/12 ,  C07D409/12 ,  A61K31/4412 ,  A61P29/00

CPC分类号： C07D213/82 ,  C07D213/81 ,  C07D279/14 ,  C07D279/22 ,  C07D307/68 ,  C07D333/70 ,  C07D401/06 ,  C07D401/12 ,  C07D409/12

摘要： Provided are compounds that are modulators of C3a receptor activity, compositions containing the compounds and methods of use of the compounds and compositions. In certain embodiments, the compounds are pyridones. In certain embodiments, provided are methods for treatment or amelioration of diseases associated with modulation of C3a receptor activity.