公开(公告)号：EP0735863A1

公开(公告)日：1996-10-09

申请号：EP95906146.0

申请日：1994-12-22

申请人： ERGO SCIENCE INCORPORATED ,  GENEVA PHARMACEUTICALS, INC.

发明人： CINCOTTA, Anthony N. ,  CINCOTTA, Manuel, Jr. ,  TIGNER, Susan Louise ,  RUNICE, Christopher Eric ,  PELLONI, Christopher Louis

IPC分类号： A61K9 ,  A61K31 ,  A61K45 ,  A61K47 ,  A61P5 ,  A61P43

CPC分类号： A61K31/4985 ,  A61K9/2013 ,  A61K31/00 ,  A61K31/475 ,  A61K31/48 ,  A61K45/06

摘要： Disclosed herein is a solid oral dosage form comprising bromocriptine and one or more pharmaceutically acceptable excipients. The oral dosage form has a dissolution rate in excess of 90 % in 5 minutes in 500 ml of 0.1N HCl aqueous medium at 37 °C and is useful for adjusting the plasma prolactin profile of a patient.

公开(公告)号：EP0735863B1

公开(公告)日：2002-11-13

申请号：EP95906146.6

申请日：1994-12-22

申请人： ERGO SCIENCE INCORPORATED ,  GENEVA PHARMACEUTICALS, INC.

发明人： CINCOTTA, Anthony N. ,  CINCOTTA, Manuel, Jr. ,  TIGNER, Susan Louise ,  RUNICE, Christopher Eric ,  PELLONI, Christopher Louis

IPC分类号： A61K9/20 ,  A61K31/44 ,  A61K31/495 ,  A61K31/48

CPC分类号： A61K31/4985 ,  A61K9/2013 ,  A61K31/00 ,  A61K31/475 ,  A61K31/48 ,  A61K45/06

摘要： Disclosed herein is a solid oral dosage form comprising bromocriptine and one or more pharmaceutically acceptable excipients. The oral dosage form has a dissolution rate in excess of 90 % in 5 minutes in 500 ml of 0.1N HCl aqueous medium at 37 °C and is useful for adjusting the plasma prolactin profile of a patient.