公开(公告)号：EP1258245A3

公开(公告)日：2003-01-02

申请号：EP02018888.4

申请日：1994-12-22

申请人： ERGO SCIENCE INCORPORATED ,  GENEVA PHARMACEUTICALS, INC.

发明人： Cincotta, Anthony N. ,  Tigner, Susan Louise ,  Pelloni, Christopher Louis ,  Cincotta, Manuel, Jr. ,  Runice, Christopher Eric

IPC分类号： A61K31/48 ,  A61K9/20 ,  A61P5/08

CPC分类号： A61K31/4985 ,  A61K9/2013 ,  A61K31/00 ,  A61K31/475 ,  A61K31/48 ,  A61K45/06

摘要： Disclosed herein is a solid oral dosage form comprising bromocriptine and one or more pharmaceutically acceptable excipients. The oral dosage form has a dissolution rate in excess of 90% in 5 minutes in 500 ml of 0.1N HCl aqueous medium at 37°C and is useful for adjusting the plasma prolactin profile of a patient.

公开(公告)号：EP1258245A2

公开(公告)日：2002-11-20

申请号：EP02018888.4

申请日：1994-12-22

申请人： ERGO SCIENCE INCORPORATED ,  GENEVA PHARMACEUTICALS, INC.

发明人： Cincotta, Anthony N. ,  Tigner, Susan Louise ,  Pelloni, Christopher Louis ,  Cincotta, Manuel, Jr. ,  Runice, Christopher Eric

IPC分类号： A61K31/48 ,  A61K9/20 ,  A61P5/08

CPC分类号： A61K31/4985 ,  A61K9/2013 ,  A61K31/00 ,  A61K31/475 ,  A61K31/48 ,  A61K45/06

摘要： Disclosed herein is a solid oral dosage form comprising bromocriptine and one or more pharmaceutically acceptable excipients. The oral dosage form has a dissolution rate in excess of 90% in 5 minutes in 500 ml of 0.1N HCl aqueous medium at 37°C and is useful for adjusting the plasma prolactin profile of a patient.

摘要翻译： 本文公开了包含溴隐亭和一种或多种药学上可接受的赋形剂的固体口服剂型。 口服剂型在37℃在500ml 0.1N HCl水性介质中在5分钟内具有超过90％的溶解速率，并且可用于调节患者的血浆催乳素特征。