公开(公告)号：EP3093027A1

公开(公告)日：2016-11-16

申请号：EP15167119.5

申请日：2015-05-11

申请人： ETH Zurich ,  Universität Zürich ,  Augurix S.A.

发明人： Leroux, Jean-Christophe ,  Rogler, Gerhard ,  Luciani, Paola ,  Estella, Ander ,  Anghel Ramond, Silvia ,  Besson Duvanel, Cécile

IPC分类号： A61K47/48 ,  A61K49/00 ,  A61K31/80 ,  C08F293/00 ,  C08F220/34 ,  C08F220/38

CPC分类号： C08F293/005 ,  A61K31/795 ,  A61K31/80 ,  A61K47/64 ,  A61K49/0021 ,  A61K49/0054 ,  C08F2220/382 ,  C08F2438/01

摘要： The present invention is directed to non-biodegradable copolymer diagnosis agent that has a low affinity for the mucosa in general and allows the transportation of specific molecules that recognizes specific target biomarkers useful in the diagnosis of a certain number of disorders such as pulmonary, gynecologic, eye and gastrointestinal diseases or disorders, and certain conditions of those diseases (such as fibrosis and inflammation), in particular inflammatory bowel disease, such as Crohn's disease or ulcerative colitis (UC) as well as coeliac disease and cancers such as colorectal cancers.

摘要翻译： 本发明涉及一般对粘膜具有低亲和力的非生物降解性共聚物诊断剂，并且允许运输识别特定目标生物标志物的特定分子用于诊断一定数量的病症如肺，妇科， 眼睛和胃肠道疾病或病症，以及那些疾病（如纤维化和炎症）的某些病症，特别是炎症性肠病如克罗恩病或溃疡性结肠炎（UC）以及乳糜泻和癌症如结肠直肠癌。