专利检索 ap:("Edigene Inc.") AND inv:"DONG, Xi" 第 1 页

1.

发明公开
GENE EDITING T CELL AND USE THEREOF 审中-公开

公开(公告)号：EP3686275A1

公开(公告)日：2020-07-29

申请号：EP18857205.1

申请日：2018-09-18

申请人： Edigene Inc.

发明人： YUAN, Pengfei , WANG, Fei , YU, Lingling , DONG, Xi

IPC分类号： C12N5/10

摘要： Provided are a universal T cell and preparation method thereof. The universal T cells comprise CAR-T and TCR-T cells, and are obtained by knocking out TCR and/or HLA and/or PD-1 proteins of T cells by a CRISPR/Cas9 genome editing technology, wherein the universal CAR-T continues to kill target cells in vivo and in vitro.